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Both the Astros and Guardians will send a southpaw to the mound on Friday, with Ronel Blanco going for the Astros and Joey Cantillo for the Guardians. First pitch from Progressive Field is set for 7:10 PM ET. MLBN is carrying the TV rights for Friday's AL matchup.

Cleveland is currently favored on the money line, with their odds sitting at -122 compared to the Astros at +103. The over/under line is at 7.5 runs, and the Guardians will be looking to extend their two-game win streak. Houston is 1st in the AL West, while Cleveland is leading the AL Central. <h3>HOUSTON ASTROS VS CLEVELAND GUARDIANS BETTING PICK</h3>The Pick: Houston Astros Moneyline +103This game will be played at Progressive Field at 7:10 ET on Friday, September 27th.<h3>HOW TO BET THE ASTROS VS GUARDIANS:</h3><ul><li>We have the Astros winning by a score of 5 to 4</li><li>If you're looking for a run line pick, we also like the Astros to cover</li><li>As for an over/under pick, we have this game finishing with 9 runs and like the over</li></ul><h3>Astros Records & Stats</h3>Houston closed out their series vs. the Mariners with a tough 8-1 loss. Heading into the game, the Astros were the +132 underdog on the money line. Things started off well for the Astros, as they got on the board with a run in the 3rd inning but gave up the lead right away as the Mariners scored three times in the top of the 3rd.

Yusei Kikuchi put together a good start for the Astros, going six innings and not giving up a run. He also issued just one walk and struck out eight Mariners. However, the Astros's offense really struggled after their 1st-inning run, and they didn't score again. Houston was also the victim of some bad luck, as the Mariners scored three runs in the 6th on a play that included a fielding error and a wild pitch.Houston is currently leading the AL West by four games over the Mariners. The Astros are 86-73 overall and went 29-23 in divisional games. The Astros are looking to bounce back today, as they dropped two of three in their series vs. the Mariners.

At home, the Astros are 46-35 this season, and they have gone 40-38 on the road. As the road underdog, the Astros have gone 16-16 this season, and their overall record in the underdog role is 19-22. So far, they have been good as the favorite, going 67-51.When the Astros are on the road, they have been a solid bet against the run line, going 43-35. They have an average run margin of +0.2 runs per game when away from home, and their overall run line record is 81-78. They have been a better bet against the run line as an underdog, going 26-15.The Houston Astros have an over/under record of 65-88 this season, with an average combined run average of 8.6 runs per game. The over/under line for today's game against the Cleveland Guardians is set at 7.5 runs, and their over/under record when the line is set at 7.5 runs is 11-19. Overall, 76.7% of their games have had higher over/under lines than 7.5 runs this season.Ronel Blanco gets the start for the Astros today as he faces the Guardians on the road. So far, he has made 28 starts and has a record of 12-6. Blanco's ERA for the season is an impressive 2.88, along with a WHIP of 1.10. In his 29 appearances, Blanco has one complete game shutout and 14 quality starts. His most recent outing came on September 21st, where he picked up the win, going six innings and giving up two earned runs. Blanco has won each of his last three outings. Per nine innings, he is averaging 9.04 strikeouts and 3.66 walks.Yordan Alvarez has been the Astros' most dangerous hitter this season, leading the team with 35 home runs and 86 RBIs. He is also batting .308, which is the 2nd best mark in the lineup. Alex Bregman has been swinging the bat well of late, going 7/22 in his last six games, with three homers and seven RBIs. For the season, Bregman is batting .256 with 26 homers.

As a team, the Astros are averaging 4.6 runs per game and are one of the league's top home run-hitting clubs. Overall, they are batting .261, which is the 3rd best mark in the majors. Houston is also near the top of the league in on-base percentage and slugging.<h3>Guardians Records & Stats</h3>Cleveland closed out their series vs. the Reds with a 5-2 win. Leading up to the game, they were the heavy favorite at -146. It was a big 1st inning for the Guardians, as they scored their first four runs in the inning. The Reds could only score two runs, both of which came in the 7th.

Andrew Walters got the start for the Guardians but only lasted 1 2/3 innings. He didn't give up a run, but the Reds pulled him in the 2nd. Cleveland's offense was carried by José Ramírez, who went 3/4 with a homer and three RBIs.Cleveland comes into today's game vs. the Astros having taken two straight games and lead the AL Central by seven games over the Royals. The Guardians are 92-67 overall and have gone 30-22 in divisional games. At home, the Guardians are 50-28 this year and 42-39 on the road.

So far, the Guardians have been favored in 98 of their games, going 64-34 in those games. As the underdog, Cleveland is 28-33 this year. They have won four straight games at home, and their overall series record is 29-16-6.The Guardians have been a solid bet against the run line this season, going 82-77 overall. They've been right around .500 at home, with a 39-39 mark, and have covered the run line in three straight games at Progressive Field. They've been a better bet on the road, going 43-38 against the run line, and have a scoring margin of +0.4 runs per game away from home.The Cleveland Guardians are playing at home against the Houston Astros today, and the over/under line for the game is set at 7.5 runs. The Guardians have had a combined run average of 8.3 runs per game this season, and their over/under record is 68-80. When the over/under line is set at 7.5 runs, their record is 18-22. Overall, 69.2% of their games have had higher over/under lines than 7.5 runs, and they are currently on a three-game under streak.Through seven starts, Joey Cantillo has a record of 2-3 and an ERA of 4.63 for the Guardians. He has made one quality start this year and is coming off an outing in which he didn't give up an earned run. Against the Rays on September 14th, Cantillo went five innings, giving up one earned run on three hits. He ended up with the win in that outing. Cantillo's ERA at home is 2.21, compared to 7.48 on the road. So far, he has allowed six homers and is averaging 9.51 strikeouts per nine innings.Jose Ramirez has been swinging a hot bat of late, going 10/24 in his last six games, including three home runs and eight RBIs. For the season, he is batting .279 with a team-high 38 homers and 115 RBIs. Josh Naylor is also a power threat in the lineup, as he is 2nd on the team with 31 homers and is batting .243.

As a team, the Guardians are averaging 4.4 runs per game, which is 14th in the league. They have been a better offensive team at home, averaging 4.7 runs per contest. Overall, they are 11th in the league in home runs and have the 16th best team batting average in the MLB.

Houston Astros vs Cleveland Guardians Betting Pick & Prediction 9/27/24

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From Fenway Park in Boston, we have the Rays and Red Sox facing off in an AL East matchup. This one gets started at 4:10 PM ET, and it is being televised on NESN. The Red Sox are favored on the money line (-122), while the Rays have a line of +104. The over/under line is currently at 8 runs.

Shane Baz is starting for the Rays, and he will be facing off against Kutter Crawford for the Red Sox. Boston comes into the game having lost two straight and is 80-80, while the Rays are 79-81 and are starting to +104.<h3>BOSTON RED SOX VS TAMPA BAY RAYS BETTING PICK</h3>The Pick: Boston Red Sox Moneyline -122This game will be played at Fenway Park at 4:10 ET on Saturday, September 28th.<h3>HOW TO BET THE RAYS VS RED SOX:</h3><ul><li>We have the Red Sox winning by a score of 5 to 4</li><li>However, if you're looking for a run line pick, we like the Rays to cover</li><li>As for an over/under pick, we have this game finishing with 9 runs and like the over</li></ul>Tampa Bay picked up a 2-1 road win over the Red Sox in the most recent game of this series. The Rays had a two-run 7th inning, and the Red Sox could only muster one run in the 8th. Heading into the game, the Rays were at +103 on the money line.

Both offenses finished the game with six hits, and the Rays actually had one more strikeout than the Red Sox with seven. Tampa Bay's two runs came on a Josh Lowe home run, while the Red Sox's lone run came on a Nick Pivetta home run.

Taj Bradley started for the Rays and picked up the win, going six innings and not giving up a run. He finished the game with seven strikeouts but issued one walk. As for the Red Sox, Pivetta went 6 2/3 innings, giving up two earned runs on four hits.<h3>Rays Records & Stats</h3>The Rays are 79-81 overall, and they trail the Yankees by 14 games in the AL East. Currently, they are in 4th place in the division, just a game behind the Red Sox for the 3rd spot. So far, they have gone 25-25 in divisional games. Tampa Bay is on the road today, and they are 37-42 away from home this season.

As the road underdog, the Rays have gone 26-31 this year, and they are 23-20-7 in series this year. Tampa Bay's overall series record is 23-20-7. They are also 37-31 as the favorite and 42-50 as the underdog this year.The Rays have been a solid bet on the run line this season, going 83-77 overall. They have been especially good on the run line on the road, going 46-33. They have covered the run line in two straight games and have been a profitable run line bet as an underdog, going 59-33.The Tampa Bay Rays have an over/under record of 66-85 this season, and their games have averaged 7.8 runs per game. When the over/under line is set at 8 runs, they have a record of 17-25-2. Overall, 46 of their games have had over/under lines set higher than 8 runs, which accounts for 28.7% of their games. Their current under streak is at 2 games.Right-hander Shane Baz is starting for the Rays today as he faces the Red Sox on the road. He has made 13 starts this year and has a record of 3-3 with a 3.07 ERA. Baz's WHIP for the season is currently 1.09. In his 13 starts, he has turned in seven quality starts and is averaging 7.61 strikeouts per nine innings. Baz most recently faced the Blue Jays, where he gave up one earned run in six innings of work. He finished with a no-decision in that outing. Before that, he had given up at least two earned runs in three straight starts.Yandy Diaz has been a bright spot for the Rays this season, as he is batting .280 and leads the team with 65 RBIs. He also has an OBP of .339. Tampa Bay's top home run hitters are Christopher Morel and Brandon Lowe, but both players are batting under .240. Morel has 21 homers and is hitting just .194, while Lowe is also at .239 and has 21 homers.

As a team, the Rays are 29th in the league in runs per game at just 3.7. They are also near the bottom of the league in most offensive categories, including on-base percentage, slugging percentage, and OPS. Over his last eight games, Jonathan Aranda is hitting .269 with three homers.<h3>Red Sox Records & Stats</h3>Boston is 80-80 overall, and they are 3rd in the AL East, 13 games behind the Yankees for the division lead. The Red Sox have gone 24-26 in divisional games this year. So far, they have dropped two straight games, and this season, they are 37-42 at home.

As the underdog, the Red Sox are 39-44 this year, and they are 41-36 as the favorite. Boston's overall series record is 25-19-6, and they have won two straight series.When betting the run line on the Red Sox, it's been more profitable to take them on the road this season. Boston is 46-35 against the run line away from Fenway Park, compared to just 30-49 at home. The Red Sox have been favored in 77 games this season, going 28-49 against the run line in those contests. When they've been the underdog, they've gone 48-35 vs. the run line.When the Boston Red Sox play at home, the over/under line is set at 8 runs. The Red Sox have an over/under record of 78-74 on the season, with an average combined run average of 9.3 runs per game. When the over/under line is set at 8 runs, their record is 15-12-3. Overall, 65.6% of their games have had higher over/under lines than 8 runs, with 105 games having higher lines and 25 games having lower lines. Currently, the under has hit in their last two games.Red Sox starter Kutter Crawford will be looking to build off his last outing, where he turned in a strong performance. Against the Twins on September 22nd, he picked up the win, going 7 2/3 innings and giving up just three earned runs. Looking at his overall numbers, Crawford has made 32 starts and has a record of 9-15. His ERA for the season is 4.17, along with a WHIP of 1.10. Opponents have a batting average of .219 vs. Crawford this season. Out of his 32 starts, he has 15 quality starts and is averaging 8.48 strikeouts per nine innings.So far this season, the Red Sox have been one of the league's best offensive teams, averaging 4.7 runs per contest, which is 9th in the MLB. They have been even better on the road, averaging 4.8 runs per game. Overall, the Red Sox are 7th in home runs and have the league's top team BABIP at .32. As a team, they are also 6th in batting average and have the 6th best slugging percentage in the league.

Jarren Duran has been swinging a hot bat of late, going 11/41 in his last 10 games. For the season, he is batting .286 and is 3rd on the team with 21 homers. Duran is also on a seven-game hitting streak. Rafael Devers leads the Red Sox with 83 RBIs and is 2nd on the team with 28 homers. Tyler O'Neill has 31 homers this season, which is the best mark on the team and 11th in the league.

Tampa Bay Rays vs Boston Red Sox Betting Pick & Prediction 9/28/24

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