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The National Football League (NFL) is easily the most popular sport in the United States, especially when it comes to betting. NFL betting puts up the biggest numbers every single year, and bettors are always looking for new betting options.

The NFL was founded all the way back in 1920 in Canton, Ohio, and that is where the Hall of Fame is located to this day. There were only a handful of teams in the league when it first started, but it didn’t take long for the league to grow.

There are now 32 teams in the NFL, and the league is broken up into two conferences and eight total divisions. Since the league just continues to be more and more popular, the league has added an extra regular season game for each team to play in.

NFL teams now play 17 total regular season games, and then the top seven teams in each conference advance to the postseason. The NFL regular season begins in September, and the Super Bowl is now played during the month of February.

When it comes to the NFL, the Super Bowl is the event that draws the most betting attention. This league isn’t going away anytime soon, and it’s actually started to become more of an international competition.

This article will not only cover the best NFL betting sites &amp; sportsbooks, but will also provide some tips on how to bet on the NFL.
<h3>Where to bet on NFL</h3>
Knowing where to find the best NFL sportsbooks is a big key if you want to have some success when wagering on this sport. Here are six of the best NFL sportsbooks to use, and all of them are going to be a little bit different.

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Best NFL Betting Sites & Sportsbooks

BetDSI

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Bet US

BetOnline

Bovada

The 2022 NFL Divisional Playoffs begin Saturday, January 22, 2022, so we are taking a closer look at the NFC showdown from Lambeau Field in Green Bay, Wisconsin, to get you the best 49ers vs. Packers betting pick and odds.



San Francisco meets Green Bay for the second time this season. Back in Week 3, the Packers outlasted the 49ers 30-28 as 3-point road underdogs to record their fourth win in the last six encounters with San Francisco. According to <a href="https://www.bangthebook.com/sportsbooks/bovada/">Bovada Sportsbook</a>, Green Bay is a firm 6-point home fave for Saturday’s contest, while the totals are listed at 47.0 points.



<h2>The Niners stunned the Cowboys in the wild-card round     </h2>



The San Francisco 49ers (11-7; 10-8 ATS) are coming off a 23-17 road victory over the Dallas Cowboys in the NFC Playoffs wild-card battle. Playing as 3.5-road underdogs, the Niners dominated the Cowboys all night long but nearly blew a 16-point lead in a chaotic finish.



Jimmy Garoppolo went 16-of-25 for 172 yards and a costly interception. Brandon Aiyuk had five receptions for 66 yards, while Elijah Mitchell and Deebo Samuel combined for 168 rushing yards and a couple of touchdowns on 37 carries.



Samuel has been outstanding in the last few weeks, scoring a TD in four of his previous five appearances. The 49ers finished the regular season in strong fashion, going 5-1 straight up and ATS over their last six contests at any location.



San Francisco has some injury worries ahead of the divisional round. Defensive end Nick Bosa is in the concussion protocol, and his eventual absence would be a massive blow for the 49ers’ defense. DL Jordan Willis (ankle) is questionable to play as well.&nbsp;



<h2>The Packers look to get back on the winning track            </h2>



The Green Bay Packers (13-4; 12-5 ATS) enjoyed two weeks of rest after finishing top of the National Football Conference. They rested most of their key players in Week 18 and suffered a surprising 37-30 defeat at the Detroit Lions to stop their five-game winning streak.



Aaron Rodgers finished the 2021 season with 4,115 yards, 37 touchdowns, and only four interceptions. It was another tremendous display by the reigning MVP, while Davante Adams had 123 receptions for 1,553 yards and 11 touchdowns.



Rodgers and Adams have been unstoppable all season. In that narrow win at San Francisco, Adams had 12 catches for 132 yards and a TD, while Rodgers tossed for 261 yards and a couple of scores.



WR Marquez Valdes-Scantling didn’t practice on Wednesday, so his status for Saturday’s clash is in limbo. Left tackle David Bakhtiari (knee) is questionable to play, too, while Randall Cobb should be back in action after missing the previous five games with a core muscle injury.



Trends:



San Francisco:



<ul><li>9-2 ATS in the last 11 games overall&nbsp;&nbsp;</li><li>5-1 ATS in the last six games against the NFC&nbsp;</li></ul>



Green Bay:



<ul><li>1-3 ATS in the last four games overall&nbsp;</li></ul>



<h2 id="h-san-francisco-49ers-vs-green-bay-packers-pick">San Francisco 49ers vs. Green Bay Packers Pick</h2>



The previous duel between the Niners and Packers was a wild one. Green Bay blew a 17-point lead on the road but managed to escape with a win thanks to Mason Crosby’s 51-yard field goal as the time expired.



I’m expecting the Packers to grab another win over San Francisco, but covering a 6-point spread could be a tricky job. The 49ers have been outstanding in the second half of the regular season, and Kyle Shanahan’s boys look ready to rumble. If Nick Bosa suits up, San Francisco’s defensive line will torture the Packers’ offensive line, as the Niners love to be physical. It seems like Jimmy Garoppolo could be the weakest link in this San Francisco team.



On the other side, Aaron Rodgers and Davante Adams will certainly continue to dominate their rivals. Still, the Packers have to put on a strong defensive performance in order to comfortably beat the Niners.



Pick: Take San Francisco 49ers +6.0 at -110&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;



The Total:



While the under is 5-1 in San Francisco’s last six outings, the over is 6-1 in Green Bay’s previous seven. When it comes to their head-to-head duels, the total has gone over in four of the previous five, and I would follow this betting trend.



The Niners will struggle to keep the Packers below 28 points. Green Bay has scored 30 or more in six of its previous seven contests. On the other side, the Packers allow 4.7 yards per carry (tied-29th in the NFL), so the 49ers know they have to run the pigskin as much as they can.



Pick: Go over 47.0 points at -110

San Francisco 49ers vs. Green Bay Packers Odds, Pick, Prediction 1/22/22

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Bookmaker

Bet US

BetOnline

Bovada