The Kansas City Chiefs take on the Tennessee Titans in Week 7 of the 2021 NFL season, as they meet each other for the first time since the 2019 AFC championship game. The Chiefs beat the Titans 35-24 en route to their Super Bowl victory, so Tennessee seeks revenge Sunday, October 24, in front of the home fans at Nissan Stadium. 

The Titans are listed as 4.5-point underdogs on BetOnline Sportsbook. The Chiefs are -210 moneyline favorites, while the totals sit at 57.5 points, as the bookies expect a proper high-scoring affair.

Kansas City had an easy job in Week 6 

The Kansas City Chiefs (3-3; 2-4 ATS) are coming off a convincing 31-13 victory at the Washington Football Team this past Sunday. They covered a 6.5-point spread to bounce back from a heavy 38-20 home loss to the Buffalo Bills in Week 5.

The Chiefs shut down the former Redskins in the second half, keeping them off the scoreboard to overcome a three-point halftime deficit. Kansas City racked up 499 total yards and yielded just 276 in a return, while Darrel Williams led the way for the Chiefs with 21 totes for 62 yards and a couple of touchdowns.

Patrick Mahomes went 32-of-47 for a couple of touchdowns and picks against Washington. He’s already recorded eight interceptions so far this season which is one of the reasons why Kansas City is 3-3 at the moment. The Chiefs’ leaky defense is another big issue, conceding 29.3 points per game (28th in the NFL) on 133.2 rushing yards (tied-26th) and 277.3 passing yards (tied-25th).

Tennessee upset Buffalo for its second straight W

The Tennessee Titans (4-2; 4-2 ATS) pulled off an upset in Week 6 and outlasted the Buffalo Bills as 6-point home underdogs, 34-31. It was their second win on the spin and fourth in the last five outings along with a surprising 27-24 overtime loss at the New York Jets.

Derrick Henry had another big game and posted 143 yards and three touchdowns on 20 carries. He’s surpassed a 100-yard mark on the ground for the fifth straight outing, and Henry has already scored ten touchdowns.

The Titans allowed Josh Allen to throw for 353 yards and three touchdowns, but they held the Bills to just 82 rushing yards (3.6 per carry). Tennessee is now yielding 26.8 points per contest (24th in the league) on 107.7 rushing yards (tied-9th) and 276.3 passing yards (24th).


Kansas City:

  • 3-13-1 ATS in the last 17 games overall
  • 1-9 ATS in the last ten games against the AFC   


  • 4-1 ATS in the last five games overall
  • 4-1 ATS in the last five games against Kansas City
  • 6-2 ATS in the last eight games played in October

Kansas City Chiefs vs. Tennessee Titans Pick

The Chiefs remain the offensive force, but their defense has been terrible as of late. Kansas City could easily struggle a lot against the Titans’ ground game, so with 4.5 points on the table, I’m going with the underdogs to cover.

Derrick Henry has been absolutely ridiculous over the last five weeks, and I don’t see him slowing down in a marquee matchup in front of the home wins. If you’re satisfied with -175 odds, go with the Titans as 7-point underdogs. The Chiefs shouldn’t blow Tennessee away even though the Titans’ secondary is a mess.

Pick: Take Tennessee Titans +4.5 at -110                

The Total:

This should be a proper high-scoring affair. Although the line is sky-high, betting on the over is a logical move. Both teams have been poor defensively so far this term, while their offensive units are capable of putting serious numbers on the scoreboard against any defense.

The over is 4-1 in the Titans’ last five games overall, and it is 4-2 in the Chiefs’ previous six outings at any location. Also, five of the last six encounters between the Titans and Chiefs in Nashville went in the over.

Pick: Go over 57.5 points at -110