Jose Abreu and the Chicago White Sox will play host to their surging division rival Cleveland Indians at Guaranteed Rate Field. The opening pitch is scheduled for 8:10 p.m. ET and NBC Sports Chicago will be televising the action.

Cleveland Indians at Chicago White Sox Odds

Chicago (+255) is coming into this contest as a really heavy underdog to Cleveland (-310) and Vegas has set the Over/Under for this night game at 9 runs (-120 for the over and +100 for the under). There's a runline of Indians -1.5 (-175) and White Sox +1.5 (+155) for this matchup. The White Sox are 68-88 straight up (SU) and 75-79 against the spread (ATS). They've gained 5.5 units for bettors taking the moneyline while gaining 8.3 units ATS. Chicago has covered the spread five times in its last seven games and the under has hit in three of those seven. The Indians are 93-64 SU and have gone 85-71 ATS. They're up 3.9 units for bettors taking the moneyline and 10.6 units ATS. Cleveland's covered the spread five times in its last seven games and the under has cashed in four of those seven. White Sox games have had an over/under record of 72-75-7 in 2019. Cleveland has been a strong under bet with a total record of 67-85-4. Shane Bieber will get the nod for the visiting Indians. The right-handed Bieber is 15-7 with a 3.23 ERA and 252 strikeouts. He's 1-1 with 21 strikeouts and a 4.58 ERA against Chicago this year (three starts). The White Sox will turn to lefty Ross Detwiler (2-5, 6.98 ERA), who has 42 strikeouts and 26 walks as well as a WHIP of 1.72. Detwiler is 0-1 with a 13.50 ERA in one start against Cleveland this year. As a unit, Chicago’s pitching staff has given up 5.3 runs per game overall this year. Its starters have a 5.39 ERA, 1.46 WHIP and 8.3 strikeouts per nine innings. The bullpen has a 4.44 ERA, 1.42 WHIP and 8.3 K/9. In 70 games against AL Central opponents, White Sox starters have an ERA of 5.19 and the bullpen's ERA is 4.69. The Chicago hitters are putting up 4.3 runs per outing, including 4.5 per game against divisional foes and 4.2 per game over their last five. The team's hit .325/.348/.495 over its last five matchups and is 3-2 SU during that stretch. The White Sox offense has been led by Jose Abreu and Tim Anderson. Abreu is slashing .281/.326/.500 with 33 home runs, 121 RBIs and 81 runs scored, while Anderson is batting .334 with 18 homers, 56 RBIs, 78 runs and 17 steals. In the visiting dugout, Cleveland’s pitchers have allowed 3.9 runs per game and its starters own a 3.67 ERA, 1.17 WHIP and 9.48 K/9. The bullpen has an ERA of 3.59, along with a WHIP of 1.17 and a K-per-9 of 9.36. Indians hitters have slashed .252/.328/.436 on their way to 4.8 runs scored per game in 2019, including 5.1 runs per game against divisional foes and 7.4 per game over the team's last five outings (4-1 SU). Shortstop Francisco Lindor and first baseman Carlos Santana continue to lead Cleveland’s hitters. Lindor is slashing .290/.342/.524 with 31 home runs, 72 RBIs, 100 runs and 22 steals, while Santana (.286/.402/.525) has produced 34 homers, 93 RBIs and 110 runs scored. The Indians have gained 3.4 units and are 31-22 ATS when facing a lefty starter this season. The over has cashed in 29 of those games, compared to 24 that've gone under in such games. On the other hand, the White Sox have lost 5.3 units and are 42-59 ATS when facing a righty starter. The over has hit in 45 of those games, compared to 52 that've gone under.

Cleveland Indians vs. Chicago White Sox MLB Pick

Predictions: SU Winner – Indians, ATS Winner – Indians, O/U – OVER

Notes

Betting Notes The under has cashed in four of Cleveland’s last seven games. The Indians have hit 12 home runs in their last 10 games, including eight over their last five. The Indians have a total OPS of .764 this season and an OPS of .753 against left-handed pitchers. The White Sox' OPS sits at .725 overall and .760 against lefties. Chicago has recorded 29.6 Runs + Hits + Errors per game over its last 10 outings and 29.4 over its last five. The Indians have won seven of their last eight games SU.