Buffalo Bills vs Denver Broncos Betting Pick & Prediction for 1/17

NFL Game preview

The Buffalo Bills travel to face the Denver Broncos in the 2025 Divisional Playoffs. This game takes place at Empower Field at Mile High in Denver. Scheduled for Saturday, January 17, 2026, the kickoff is at 4:30 PM and will be shown on CBS.

The weather forecast predicts a very cold day, but the skies will be clear. The Bills come in with a 1-0 postseason record, while the Broncos had a strong regular season with a 14-3 record. Denver’s home advantage is notable with an 8-1 home record this season.

Buffalo Bills Team Preview

The Buffalo Bills come into this game with a strong record in recent weeks. In their last five games, they have secured four wins, including a dominant 35-8 victory over the New York Jets. Their offense looked sharp, with Mitchell Trubisky throwing for 259 yards and four touchdowns in that game.

In the 2025 season, Josh Allen has been a key player for the Bills. He has thrown for 3,668 yards and 25 touchdowns, leading the league in fantasy points among quarterbacks. James Cook has also been a standout, leading the league with 1,621 rushing yards and adding 12 touchdowns.

The Bills have some injury concerns heading into this matchup. Key players like Josh Allen, Matt Milano, and Ty Johnson are listed as questionable. Despite these injuries, the Bills have depth in their roster to compete at a high level.

Bills vs Broncos Game Day Info

  • Sport: NFL
  • Teams: Buffalo Bills vs. Denver Broncos
  • Venue: Empower Field at Mile High, Denver, CO
  • Date: Saturday, January 17, 2026
  • Betting Odds: Bills Moneyline -109, Broncos Moneyline -110

Denver Broncos Team Preview

The Denver Broncos recently had a successful game against the Los Angeles Chargers. They won with a score of 19-3 at Empower Field at Mile High. Bo Nix, the quarterback, had 141 passing yards, while the defense was strong with an interception by Ja’Quan McMillian.

In a previous game, the Broncos defeated the Kansas City Chiefs 20-13. They played at Arrowhead Stadium and recorded 175 passing yards. Bo Nix threw one touchdown, and the defense held the Chiefs to only 10 first downs.

Before these wins, the Broncos faced a loss against the Jacksonville Jaguars, 34-20. They had 344 passing yards in that game. RJ Harvey contributed with 50 rushing yards and one rushing touchdown at Empower Field at Mile High.

BTB Betting Pick

The Bills are favored by 1.5 points against the Broncos. With the Bills’ strong offense, ranked 2nd in scoring, they are likely to cover the spread. The projected score is Bills 27, Broncos 24, which supports taking the Bills to cover.

The total for the game is set at 46.0 points. The Bills and Broncos have solid offenses, ranking 2nd and 10th in scoring, respectively. The projected total score of 51 points suggests taking the over.