Jacksonville Jaguars vs Tennessee Titans Prediction & Odds – November 15, 2026

Jacksonville visits Tennessee at Nissan Stadium with a clear gap in their regular-season records. The Jaguars bring a 6-2 mark into Nashville, while the Titans seek their first home win after an 0-4 start there.

Game details and odds

Sunday, November 15, 2026 at 1:00 pm EST · Nissan Stadium

Total: 46.5 — over -110, under -110.

Draft Kings odds checked November 12, 2026 16:01 UTC. Odds subject to change.

Jacksonville’s offense meets a vulnerable defense

Jacksonville averages 28.6 points per game, and Trevor Lawrence has thrown 18 touchdowns against four interceptions. The Jaguars also allow 15.1 points per game, giving them a path to control the matchup on both sides. Their 2-1 road record suggests that production has not depended entirely on playing at home.

The Jaguars have built momentum with emphatic wins over Indianapolis and Baltimore, scoring 42 and 33 points while holding those opponents to seven and 10. The Baltimore result came on the road, an encouraging sign for this trip. Their recent stretch has not been flawless: Houston beat them 34-31 at neutral-site Wembley Stadium. That loss showed Jacksonville can be drawn into a close, high-scoring game, even as its two subsequent results demonstrated a stronger defensive response. Earlier wins over Philadelphia in London and Cincinnati on the road add variety to that stretch.

Tennessee’s scoring uptick faces a tougher test

Tennessee averages 18.0 points and 284.9 yards per game, so sustaining drives is a central challenge against Jacksonville. Tony Pollard has 595 rushing yards and six touchdowns, offering one route to a steadier offense. Defensively, the Titans allow 396.9 yards per game, leaving little margin for another uneven performance.

The Titans have shown more scoring potential in their latest outings, putting up 36 at Cincinnati and 24 against Cleveland, but lost both games. Cincinnati scored 43, making Tennessee’s biggest recent offensive output insufficient. A 26-20 road win over Indianapolis showed the Titans can finish a close contest; their home results against Cleveland and Houston tell a less encouraging story. Houston held them to three points in a 26-3 defeat. Tennessee needs the attack that appeared against Cincinnati without the defensive breakdown that accompanied it, a balance these results have yet to establish.

Injury news

Jacksonville Jaguars: B.J. Green II – Injured Reserve (Elbow); Travon Walker – Questionable (Ribs); Antonio Johnson – Questionable (Ankle); Branson Combs – Questionable (Shoulder); Robert Hainsey – Questionable (Concussion).

Tennessee Titans: JC Latham – Questionable; Tommy Townsend – Out; Jaylon Jones – Out; Cody Barton – Questionable (Concussion); Anthony Hill Jr. – Questionable (Neck).

Availability checked November 12, 2026 16:01 UTC. Reported statuses may change; final lineups are not confirmed here.

BTB Betting Pick

Winner pick: Jacksonville Jaguars.

Jacksonville’s recent road win at Baltimore and strong scoring give it the edge over a Tennessee side that has struggled at home. The Titans’ recent offensive improvement keeps an upset possible.

Original winner pick recorded November 12, 2026 10:01 UTC. Subsequent updates retain that selection.