New England Patriots vs Detroit Lions Prediction & Odds – November 15, 2026
Detroit Lions to win Moneyline -155
Bet Detroit Lions at BetOnlineOdds checked Nov 12, 11:01 AM ET. Prices vary by sportsbook, so compare before you bet.
18+ · Gambling problem? Call 1-800-GAMBLER
Detroit and New England meet at FC Bayern Munich Stadium in a neutral-site matchup that puts two productive offenses under scrutiny. The designated-home Lions bring the stronger record, but the Patriots have ways to challenge them.

Game details and odds
Sunday, November 15, 2026 at 9:30 am EST · FC Bayern Munich Stadium (neutral venue, Munich)
| Team | Spread (American price) | Moneyline |
|---|---|---|
| New England Patriots | +2.5 (+100) | +130 |
| Detroit Lions | -2.5 (-120) | -155 |
Total: 51.5 — over +100, under -120.
Draft Kings odds checked November 12, 2026 16:01 UTC. Odds subject to change.
New England's passing game meets a defensive test
New England averages 380.9 yards and 23.4 points per game, with 261.0 yards coming through the air. Drake Maye has thrown for 2,282 yards and 18 touchdowns, though his 11 interceptions give Detroit a potential opening. The Patriots allow 23.0 points per game, keeping their defensive work central to the matchup.
The Patriots' recent results show both their scoring capacity and the cost of defensive lapses. They put up 45 points against Las Vegas and followed with a win over the Jets, but a loss at Chicago interrupted that run. A 24-19 win at Miami showed they can get through a tighter game away from home. Most recently, Green Bay scored 45 in New England despite the Patriots producing 27. That contrast makes their response after a difficult defensive outing a major question entering this meeting.
Our pick: Detroit Lions to win.
Bet Detroit Lions at BetOnlineDetroit's balance faces a tighter scoring trend
Detroit averages 27.8 points and 395.9 yards per game, supported by 268.1 passing yards and 127.8 rushing yards. Jared Goff has 15 touchdown passes against two interceptions, while Jahmyr Gibbs has 847 rushing yards and nine touchdowns. That balance could help the Lions avoid relying on one route to sustained offense.
The Lions have won four straight in their listed results, but their last three victories came with 20 points or fewer scored. They edged Green Bay 20-17, beat Minnesota 19-15 and then held Miami to nine points in a 19-9 road win. Those games suggest Detroit can win without a high-scoring performance, an important counterweight to its earlier 45-point showing against Arizona. The loss to Carolina before that run is a reminder that Detroit has not controlled every recent matchup, even when it has found ways to close out tight contests.
Injury news
New England Patriots: TreVeyon Henderson – Out (Illness); A.J. Brown – Questionable (Knee); Charles Woods – Questionable (Hamstring); Ben Brown – Out (Knee); Will Campbell – Questionable.
Detroit Lions: D.J. Reed – Questionable (Hip); Kerby Joseph – Out (Knee); Brian Branch – Questionable (Hip); Jacob Saylors – Out; Sione Vaki – Questionable (Ankle).
Availability checked November 12, 2026 16:01 UTC. Reported statuses may change; final lineups are not confirmed here.
BTB Betting Pick
Winner pick: Detroit Lions.
Detroit's balanced production and three consecutive wins in lower-scoring games give it the edge. New England's ability to score keeps this competitive, but its latest defensive showing leaves more uncertainty on that side.
Original winner pick recorded November 12, 2026 09:02 UTC. Subsequent updates retain that selection.
More NFL picks for November 15
- Pittsburgh Steelers vs Cincinnati Bengals Prediction & Odds
- Los Angeles Rams vs Arizona Cardinals Prediction & Odds
- Seattle Seahawks vs Las Vegas Raiders Prediction & Odds
- Buffalo Bills vs New York Jets Prediction & Odds
- Carolina Panthers vs New Orleans Saints Prediction & Odds
- Miami Dolphins vs Indianapolis Colts Prediction & Odds
- Jacksonville Jaguars vs Tennessee Titans Prediction & Odds
- Minnesota Vikings vs Green Bay Packers Prediction & Odds