Oklahoma State Cowboys vs Arizona Wildcats Betting Pick & Prediction for 10/4

College Football Preview

In Week 6 of the 2025 regular season, the Oklahoma State Cowboys travel to Arizona Stadium to take on the Arizona Wildcats. The game is set for Saturday, October 4th, at 3:00 PM and will be broadcast on TNT. The Cowboys have a season record of 1-3, while the Wildcats stand at 3-1.

Oklahoma State has struggled on the road this season, with a 0-1 record away from home. On the other hand, Arizona is undefeated at home with a 3-0 record. The odds show Oklahoma State as the underdog with a moneyline of +765, and Arizona has a moneyline of -1285. The spread favors Arizona by 20.5 points.

Oklahoma State Team Preview

The Oklahoma State Cowboys have had a rough start to their 2025 season. They have lost three of their four games. Their only win came against the UT Martin Skyhawks, where they won 27-7.

In recent games, the Cowboys faced challenges on both sides of the ball. Against the Baylor Bears, they lost 45-27, allowing 393 passing yards. Their defense also struggled against the Oregon Ducks, with a 69-3 loss and giving up 312 rushing yards.

The Cowboys have also been hit with several injuries. Key players like Markell Samuel and Freddie Brock IV are out or questionable. This has added to their challenges on the field this season.

Oklahoma State vs Arizona Game Day Info

  • Sport: NCAA Football
  • Teams: Oklahoma State Cowboys vs. Arizona Wildcats
  • Venue: Arizona Stadium in Tucson, AZ
  • Date: Saturday, October 4, 2025
  • Betting Odds: Oklahoma State +765, Arizona -1285

Arizona Team Preview

The Arizona Wildcats have shown mixed results in recent games. They had a tough game against Iowa State, losing 39-14. In that game, they had 253 passing yards but gave up 288 passing yards to Iowa State. The Wildcats also had two interceptions, which hurt their chances.

Arizona had better luck at home against Kansas State and Weber State. They won against Kansas State 23-17, with 178 passing yards and 237 rushing yards. The Wildcats dominated Weber State, winning 48-3 with an impressive 406 passing yards.

Arizona’s top players have made a mark this season. Quarterback Noah Fifita has 965 passing yards and eight touchdowns over four games. Running back Ismail Mahdi leads with 348 rushing yards, while receiver Javin Whatley has 264 receiving yards. The Wildcats face injury concerns with key players like Tyler Powell and Tre Spivey dealing with injuries.

BTB Betting Pick

For the spread pick, Oklahoma State is given a +20.5 point spread. Arizona’s defense ranks 36th in points against, while Oklahoma State’s offense ranks 85th in points for. With this in mind, Oklahoma State is likely to cover the spread of +20.5.

For the over/under pick, the total is set at 55.5 points. Arizona has scored 125 points this season, while Oklahoma State has allowed 140 points. These stats suggest the game will go over the total of 55.5 points.