Detroit Lions vs Cincinnati Bengals Betting Pick & Prediction for 10/5

NFL Game preview

The Detroit Lions head to Paycor Stadium to take on the Cincinnati Bengals in Week 5 of the 2025 NFL season. The game will take place on Sunday, October 5, at 4:25 PM and will be broadcast on FOX. Fans can expect a clear sky and mild weather for this afternoon game in Cincinnati.

The Lions come into this game with a 3-1 record. They have performed well at home, winning both of their games, and have split their road games 1-1. On the other side, the Bengals hold a 2-2 record, winning their only home game so far. This game will be an opportunity for both teams to improve their standings early in the season.

Detroit Lions Team Preview

The Detroit Lions have had a strong start to the 2025 season. They won their last three games, scoring 34-10 against the Browns, 38-30 against the Ravens, and 52-21 against the Bears. Their only loss came in Week 1 against the Packers, with a score of 27-13.

Jared Goff has been a key player for the Lions. He has thrown for 929 yards, 9 touchdowns, and 2 interceptions over four games. Amon-Ra St. Brown leads the team in receiving with 307 yards and 6 touchdowns.

The Lions’ defense has also been effective. Aidan Hutchinson and Al-Quadin Muhammad have been strong on the defensive line, contributing to the team’s sack total. Despite several injuries, the Lions have managed to maintain their performance, but they will need to manage their roster carefully moving forward.

Lions vs Bengals Game Day Info

  • Sport: NFL
  • Teams: Detroit Lions vs. Cincinnati Bengals
  • Venue: Paycor Stadium in Cincinnati, OH
  • Date: Sunday, October 5, 2025
  • Betting Odds: Lions Moneyline -566, Bengals Moneyline +416, Lions Spread -10.5 (-105), Bengals Spread +10.5 (-115), Total Over 49.5 (-109), Total Under 49.5 (-111)

Cincinnati Bengals Team Preview

The Cincinnati Bengals have faced a challenging start to the 2025 season. They have a record of 2-2 after four games. They began the season with a close win against the Cleveland Browns, securing a 17-16 victory.

Offensively, the Bengals have struggled in recent games. Against the Denver Broncos, they only managed 3 points. The team has been dealing with injuries, including their starting quarterback, Joe Burrow, who is out due to a toe injury.

On defense, the Bengals have shown some strengths but also weaknesses. They allowed the Minnesota Vikings to score 48 points in Week 3. Players like Demetrius Knight Jr. have been key contributors, but the team will need more consistency moving forward.

BTB Betting Pick

The Lions are favored by 10.5 points against the Bengals. The Lions have the top-ranked offense, scoring 564 points last season. The Bengals’ defense allowed 434 points, ranking 24th. With the Lions’ strong offense and Bengals’ weaker defense, the Lions should cover the -10.5 spread.

The total for the game is set at 49.5 points. The Lions and Bengals combined for 1,036 points last season. Both teams have high-powered offenses, and the Bengals’ defense ranked low in points allowed. This suggests the game could exceed 49.5 points, making the over a good pick.