Washington Commanders vs Los Angeles Chargers Betting Pick & Prediction for 10/5

NFL Game preview

The Washington Commanders will travel to face the Los Angeles Chargers in a Week 5 game of the 2025 NFL season. The game will take place at SoFi Stadium in Inglewood, California, under a clear sky. Kickoff is scheduled for Sunday, October 5, 2025, at 4:25 PM, and fans can catch the action on FOX.

The Commanders enter this game with a 2-2 record, having won both of their home games but losing on the road. Under the guidance of head coach Dan Quinn, they aim to secure their first road victory. The Chargers, led by head coach Jim Harbaugh, have a strong 3-1 record and remain unbeaten at home. They will look to continue their solid performance in front of their home crowd.

Washington Commanders Team Preview

The Washington Commanders have shown mixed results in the early games of the season. In Week 4, they lost to the Atlanta Falcons 34-27. The Commanders had 147 passing yards and 147 rushing yards, but struggled with turnovers, fumbling four times.

In Week 3, the Commanders put up a strong performance against the Las Vegas Raiders, winning 41-24. They matched the Raiders with 17 first downs and had a balanced offense with 199 passing yards and 201 rushing yards. Marcus Mariota led the team with 207 passing yards and one touchdown.

The Commanders have faced challenges with injuries, impacting key players. Terry McLaurin and Austin Ekeler are among those ruled out, affecting their offensive strength. Deebo Samuel Sr. is questionable with a heel injury, which could impact their receiving options in the upcoming game.

Commanders vs Chargers Game Day Info

  • Sport: NFL
  • Teams: Washington Commanders vs. Los Angeles Chargers
  • Venue: SoFi Stadium in Inglewood, CA USA — Dome
  • Date: Sunday, October 5, 2025
  • Betting Odds: Commanders +133, Chargers -158, Spread: Commanders +3.0 (-112), Chargers -3.0 (-107), Total Over/Under: 47.0

Los Angeles Chargers Team Preview

The Los Angeles Chargers are looking to make an impact this season. Justin Herbert leads the team with impressive stats. He has 1,063 passing yards and seven touchdowns in four games. Herbert ranks first in passing yards and touchdowns among his teammates.

Omarion Hampton is a key player in the running game. He has 270 rushing yards and two touchdowns. Hampton also contributes with 14 receptions, showing his versatility on the field.

Injuries are a concern for the Chargers. Key players like Khalil Mack and Rashawn Slater are on the injured reserve list. Derwin James Jr. is questionable for the next game, impacting the defense’s performance. The team will need others to step up in their absence.

BTB Betting Pick

The Commanders are getting a +3.0 spread against the Chargers. With the Commanders’ strong offense, ranked 5th in scoring, they have a good chance to cover the spread. The projected score is Commanders 27, Chargers 24, making the Commanders a solid pick to cover the +3.0 spread.

The total for this game is set at 47.0. The Commanders’ offense is ranked high, while the Chargers have the top-ranked defense. However, the projected score is Commanders 27, Chargers 24, which totals 51 points. This suggests the game will go over the 47.0 line.