Syracuse Orange vs SMU Mustangs Betting Pick & Prediction for 10/4

College Football Preview

Week 6 of the 2025 regular season brings an afternoon game between the Syracuse Orange and the SMU Mustangs. The game will take place at Gerald J. Ford Stadium in Dallas, Texas. Fans can catch the action live on the ACCN channel at 3:30 PM.

Syracuse heads into the game with a 3-2 record. They have won all their road games so far this season. SMU, the home team, has a 2-2 record and is looking to improve their 1-1 home record. Both teams are part of the Atlantic Coast Conference.

Syracuse Team Preview

Syracuse Orange had a mixed start to their season. They lost their most recent game to Duke Blue Devils 38-3. Before that, they grabbed a win against Clemson Tigers with a score of 34-21.

The team has been strong in passing, ranking 5th in the nation. Steve Angeli, their top QB, is out with an Achilles injury. This could affect their passing game in the coming weeks.

On the ground, Syracuse ranks 97th in rushing yards. Yasin Willis leads the running backs with 296 rushing yards. The team will need more production from the backfield to balance their offense.

Syracuse vs SMU Game Day Info

  • Sport: NCAA Football
  • Teams: Syracuse Orange vs. SMU Mustangs
  • Venue: Gerald J. Ford Stadium, Dallas, TX
  • Date: Saturday, October 4, 2025
  • Betting Odds: Syracuse +573, SMU -844, Spread: Syracuse +17.5 (-111), SMU -17.5 (-108), Total Over/Under: 57.5

SMU Team Preview

SMU Mustangs had a mixed start to their 2025 season. They began strong with a 42-13 win against East Texas A&M Lions at home. In Week 2, they faced a close game but fell short, losing 48-45 to Baylor Bears, also at home.

In Week 3, the Mustangs secured a victory against Missouri State Bears with a 28-10 score. The game was played away at Robert W. Plaster Stadium. Their performance showed strong control, as they had more first downs and rushing yards than the Bears.

Week 4 was challenging for SMU, as they lost 35-24 against TCU Horned Frogs. The game took place at Amon G. Carter Stadium. Despite gaining 290 passing yards, they struggled with two interceptions, affecting their outcome.

BTB Betting Pick

For the spread pick, SMU is favored by 17.5 points against Syracuse. Syracuse has shown a strong passing offense, ranking 5th this season. However, their defense ranks 103rd in points against, which could be problematic. SMU’s defense is stronger, ranking 73rd in points against. With these factors, SMU should cover the -17.5 spread. The projected score is SMU 38, Syracuse 17.

For the over/under pick, the total is set at 57.5 points. Syracuse’s defense allows a lot of points, but SMU’s defense is better. Both teams have decent offenses, but not top-tier. A projected total of 55 points suggests taking the under. The projected score is SMU 38, Syracuse 17, totaling 55 points.