Kansas City Chiefs vs Jacksonville Jaguars Betting Pick & Prediction for 10/6

The Kansas City Chiefs are set to play against the Jacksonville Jaguars in Week 5 of the 2025 NFL season. The game will take place at EverBank Stadium in Jacksonville, Florida. The kickoff is scheduled for Monday night at 8:15 PM, and it will be broadcast on ABC.
The Chiefs, led by head coach Andy Reid, have a record of 2-2. They are looking to improve their standings in the AFC West. Meanwhile, the Jaguars, coached by Liam Coen, hold a 3-1 record and are strong at home this season. The weather forecast predicts a warm day with light rain, which could impact the gameplay on the outdoor field. The consensus odds favor the Chiefs with a moneyline of -185.
Kansas City Chiefs Team Preview
The Kansas City Chiefs have a strong start to their season. In Week 4, they secured a win against the Baltimore Ravens with a score of 37-20. Patrick Mahomes had an impressive game with 270 passing yards and four touchdowns.
In Week 3, the Chiefs won against the New York Giants with a score of 22-9. Mahomes threw for 224 yards and one touchdown. Tyquan Thornton was a key player with a touchdown reception.
The Chiefs faced a setback in Week 2 against the Philadelphia Eagles, losing 20-17. Mahomes managed 187 passing yards with one touchdown. Despite the loss, the defense kept the Eagles’ passing game under 100 yards.
Chiefs vs Jaguars Game Day Info
- Sport: NFL
- Teams: Kansas City Chiefs vs. Jacksonville Jaguars
- Venue: EverBank Stadium in Jacksonville, FL USA
- Date: Monday, October 6, 2025
- Betting Odds: Chiefs Moneyline -185, Jaguars Moneyline +155
Jacksonville Jaguars Team Preview
The Jacksonville Jaguars are having a strong season. They have won three of their last four games. Their offense has been led by quarterback Trevor Lawrence and running back Travis Etienne Jr.
Lawrence has thrown for 845 yards with five touchdowns in four games. Etienne has been effective on the ground with 394 rushing yards. The team has shown improvement from last season’s offensive ranks.
On defense, the Jaguars have made key plays with interceptions and fumbles recovered. Devin Lloyd and Foyesade Oluokun have been standout players. The defense will need to continue its solid play against upcoming opponents.
BTB Betting Pick
The Chiefs are favored by 3.5 points against the Jaguars. The Chiefs have a strong defense, ranked 4th in opponent scoring, while the Jaguars rank 25th. The Chiefs’ offense also ranks higher than the Jaguars. Therefore, picking the Chiefs to cover the spread at -3.5 seems reasonable. Projected score: Chiefs 27, Jaguars 20.
The total for the game is set at 46.5 points. The Chiefs have a solid defense, and the Jaguars’ offense ranks low, which may limit scoring. Considering these factors, the under 46.5 points is a reasonable choice. Projected total score: 47 points.