Pittsburgh Pirates vs New York Yankees Betting Pick & Prediction for Game on 7/22

MLB game preview

The Pittsburgh Pirates and New York Yankees are set to play at Yankee Stadium. The Pirates hold a record of 52-49, placing them third in the NL Central. They have won 6 out of their last 10 games but are coming off a loss.

The Yankees have a record of 56-44, ranking them second in the AL East. They have won their last two games and also have a 6-4 record in their last 10. The game will start at 1:05 PM on July 22, 2026, and will be broadcast on SN LA.

Pittsburgh Pirates Team Preview

The Pittsburgh Pirates are heading into their next game with Mitch Keller as their probable starting pitcher. Keller has a season record of 6 wins and 7 losses with a 5.14 ERA. He has struck out 77 batters so far.

In their recent game against the Yankees, the Pirates lost by a score of 8-5. Braxton Ashcraft started on the mound and gave up 7 earned runs over 3 innings. Esmerlyn Valdez hit a home run and had 2 RBIs.

The Pirates’ hitting lineup is led by Brandon Lowe, who has 21 home runs and 65 RBIs. Nick Gonzales is another key player with a batting average of .309. Esmerlyn Valdez has also been strong, with a .306 batting average and 13 home runs.

Pirates vs Yankees Game Day Info

  • Sport: MLB
  • Teams: Pittsburgh Pirates vs. New York Yankees
  • Venue: Yankee Stadium in New York, NY
  • Date: Wednesday, July 22, 2026
  • Betting Odds: Pirates Moneyline +139, Yankees Moneyline -165

New York Yankees Team Preview

The New York Yankees have had a mix of wins and losses in recent games. On July 20th, they secured a win against the Pittsburgh Pirates with a score of 8-5. Jazz Chisholm Jr. made a significant impact with two home runs and five RBIs.

In the season, the Yankees rank high in slugging percentage and home runs. They have a team slugging percentage of .423, which places them fourth. They have hit 146 home runs, ranking them second in the league.

The Yankees’ pitching staff has shown strength with a team ERA of 3.42, the best in the league. Gerrit Cole is set to start the next game against the Pirates. He has a season ERA of 3.93 and 55 strikeouts.

BTB Betting Pick

The Yankees are favored to win with a moneyline of -165. They have a strong pitching staff with the best ERA in the league at 3.42. The Pirates have a higher batting average, but the Yankees’ pitching edge makes them the pick to win. The projected score is Yankees 5, Pirates 4.

The total for the game is set at 9.5 runs. Both teams have shown the ability to score, but the Yankees’ pitching might limit the runs. The Pirates also have a solid offense, ranked first in batting average. The projected total is 9 runs, so the pick is to go under 9.5.