Baltimore Orioles vs Boston Red Sox Betting Pick & Prediction for 7/22

MLB game preview

The Baltimore Orioles and the Boston Red Sox are set to meet at Fenway Park for an afternoon game on July 22, 2026. The Orioles hold a record of 49-52 and are currently fourth in the AL East. They have been strong lately, winning 7 of their last 10 games.

The Red Sox come into this game with a record of 51-48 and sit third in the division. They are riding a 14-game winning streak and have won all their last 10 games. Dean Kremer is set to pitch for the Orioles, while Jake Bennett will take the mound for the Red Sox.

Baltimore Orioles Team Preview

The Baltimore Orioles have shown strong performances in recent games. They managed to win three out of their last five games. Notably, they secured a 5-2 victory over the Houston Astros with Brandon Young delivering seven solid innings on the mound.

Offensively, Pete Alonso stands out with 21 home runs and 66 RBIs this season. Gunnar Henderson and Samuel Basallo also contribute with 17 and 16 home runs, respectively. The team’s batting average is .238, ranking 16th in the league.

On the pitching side, Dean Kremer is expected to start in the next game. He has a 4.15 ERA with 29 strikeouts this season. The Orioles’ overall team ERA is 4.22, which ranks 14th in the league.

Orioles vs Red Sox Game Day Info

  • Sport: MLB
  • Teams: Baltimore Orioles vs. Boston Red Sox
  • Venue: Fenway Park in Boston, MA
  • Date: Wednesday, July 22, 2026
  • Betting Odds: Orioles Moneyline +118, Red Sox Moneyline -140

Boston Red Sox Team Preview

The Boston Red Sox have been on a winning streak at home. They recently secured a close 6-5 victory against the Baltimore Orioles. Payton Tolle started the game, pitching 5 2/3 innings with nine strikeouts.

In their game against the Tampa Bay Rays on July 19th, the Red Sox won 6-1. Sonny Gray pitched six innings, allowing only one earned run. Willson Contreras was a key player, hitting a home run and driving in two runs.

On July 17th, the Red Sox dominated the Rays with a 10-0 win. Jake Bennett pitched six scoreless innings, giving up only one hit. The team had 15 hits, including home runs from Carlos Narváez and Masataka Yoshida.

BTB Betting Pick

The Red Sox are the pick to win the game with a moneyline of -140. They have a strong pitching record with a 3.55 ERA, ranking 4th. The Orioles’ pitching ranks 14th with a 4.22 ERA, which gives the Red Sox an edge at home.

The over/under line is set at 9.0. Both teams have solid hitting stats, but the Red Sox have a better overall batting average and on-base percentage. Considering the pitching and hitting stats, the projected total score leans toward going under 9.0.