Philadelphia 76ers vs Boston Celtics Betting Pick & Prediction for 4/21

The Boston Celtics and Philadelphia 76ers are set for Game 2 of their Eastern Conference First Round series. The Celtics have the edge with a 1–0 lead after their win at TD Garden. The game is on Tuesday, April 21, 2026, at 7:00 PM, and it will be shown on NBC.

Philadelphia, led by Coach Nick Nurse, seeks to even the series. The 76ers ended the regular season with a 45-37 record and are looking to bounce back from their 91-123 loss. On the other side, the Celtics, under Coach Joe Mazzulla, finished second in the Eastern Conference with a 56-26 record. They aim to extend their lead in front of their home crowd.

76ers vs Celtics Game Day Info

  • Sport: NBA
  • Teams: Philadelphia 76ers vs. Boston Celtics
  • Venue: TD Garden
  • Date: Tuesday, April 21, 2026
  • 76ers Spread: +13.5 (-111)
  • Celtics Spread: -13.5 (-111)
  • 76ers MoneyLine: +605
  • Celtics MoneyLine: -908
  • Over/Under: 216 (-110)

Philadelphia 76ers Team Preview

The Philadelphia 76ers had a tough game against the Boston Celtics, losing 123-91. Tyrese Maxey led the team with 21 points and 8 assists. VJ Edgecombe contributed 13 points, while Paul George added 17 points to the team’s effort.

In their previous game, the 76ers won against the Orlando Magic with a score of 109-97. Tyrese Maxey was impressive, scoring 31 points and providing 6 assists. Andre Drummond also played well, securing 14 points and grabbing 10 rebounds.

During the regular season, Tyrese Maxey was a standout player for the 76ers. He averaged 28.3 points and 6.6 assists per game. Joel Embiid also contributed significantly but is currently out due to an illness.

Boston Celtics Team Preview

The Boston Celtics are on a strong run. In their recent game against the Philadelphia 76ers, they won by 32 points with a score of 123-91. Jayson Tatum and Jaylen Brown led the team with 25 and 26 points, respectively.

Looking at the season stats, the Celtics score an average of 123 points per game, ranking second. They are fifth in possessions per game, showing a fast-paced style. Their field goal percentage stands at 50%, placing them sixth.

Defensively, the Celtics are solid, allowing only 91 points per game, which is second-best. They are first in effective field goal percentage allowed at 41.1%. They also limit opponents to just 4 three-pointers made per game, which is the best in the league.

BTB Betting Pick

The Celtics are favored by 13.5 points against the 76ers. Boston scores 123 points per game and allows 91, while Philadelphia scores 100 and allows 110. With a strong offense and defense, the Celtics should cover the spread. Pick: Celtics -13.5.

The total for the game is set at 216 points. Boston and Philadelphia have combined averages of 223 points per game. Despite Boston’s strong defense, the offensive firepower suggests the total will go over. Pick: Over 216.