North Carolina State Wolfpack vs Pittsburgh Panthers Betting Pick & Prediction for 10/25

In Week 9 of the 2025 regular season, the North Carolina State Wolfpack will visit the Pittsburgh Panthers. The game will take place at Acrisure Stadium in Pittsburgh, Pennsylvania. Fans can catch the action on ACCN at 3:30 PM on Saturday, October 25.
The Wolfpack come into this game with a 4-3 record. They have performed better at home with a 3-1 record, but they are 1-2 on the road. The Panthers, meanwhile, hold a 5-2 record. At home, they have a 3-1 record, matching their success on the road with a 2-1 record.
North Carolina State Team Preview
North Carolina State Wolfpack have had a mixed season so far. They have won two games and lost three in their recent matchups. The team had a big win against Campbell with a score of 56-10 but struggled in other games like the loss to Notre Dame, 36-7.
Quarterback CJ Bailey leads the team with 1,846 passing yards and 14 touchdowns. Hollywood Smothers is their top running back, gaining 739 rushing yards and scoring five touchdowns. Terrell Anderson is the leading wide receiver with 445 receiving yards and four touchdowns.
Injuries have impacted the team, with several players listed as questionable or out. Key players like Isaiah Crowell and Terrente Hinton are not expected to play. This might affect the team’s performance in upcoming games.
North Carolina State vs Pittsburgh Game Day Info
- Sport: NCAA Football
- Teams: North Carolina State Wolfpack vs. Pittsburgh Panthers
- Venue: Acrisure Stadium in Pittsburgh, PA
- Date: Saturday, October 25, 2025
- Betting Odds: Pittsburgh -247, North Carolina State +200
Pittsburgh Team Preview
The Pittsburgh Panthers are coming off a strong win against Syracuse. They scored 30 points while allowing only 13. Pittsburgh’s defense grabbed three interceptions, helping them secure the victory.
Earlier, the Panthers had a close game with Florida State. They won 34-31 in a tough contest. Their passing game was on point with 321 yards.
Pittsburgh faced Boston College at home and dominated. The Panthers scored 48 points and allowed just 7. Their offense was effective with 331 passing yards and 172 rushing yards.
BTB Betting Pick
For the spread, Pittsburgh is favored by 6.5 points. Given their strong offensive performance, ranked 11th in points for, and North Carolina State’s defensive struggles, ranked 101st in points against, Pittsburgh is likely to cover the spread. The projected score could be Pittsburgh 31, North Carolina State 24.
The total for the game is set at 56.5 points. Pittsburgh’s offense, which ranks 11th in scoring, combined with North Carolina State’s defense, which allows a high number of points, suggests the total will go over. Expect a combined score around 55, close to the set line.