Los Angeles Rams vs San Francisco 49ers Betting Pick & Prediction 12/12/24

The 49ers are favored at -144 on the money line as they host the Rams at 8:15 ET on Thursday, December 12th at Levi’s Stadium in Santa Clara, CA. This week 15 NFC West matchup is being televised by AMZN, and the 49ers are -2.5 point favorites, with the over/under line set at 48.5 points. The 49ers and Rams are both looking to improve their records in this one.
LOS ANGELES RAMS VS SAN FRANCISCO 49ERS BETTING PICK
The Pick: San Francisco 49ers -2.5
This game will be played at Levi’s Stadium at 8:15 ET on Thursday, December 12th.
WHY BET THE SAN FRANCISCO 49ERS:
- We have the 49ers winning this one by a score of 22 to 19
- Not only do we have the 49ers winning straight-up, we have them covering the spread at -2.5
- We see this game finishing below the line of 48.5 points
Will The Rams Pick Up A Win On The Road?
With two straight wins, the Rams have improved to 7-6, putting them 2nd in the NFC West and 8th in the conference standings. After a week 12 loss to the Eagles, they bounced back by beating the Saints in week 13 and then edged out the Bills 44-42 in week 14. The Rams were 3.5-point underdogs against Buffalo but managed to cover the spread, bringing their ATS record to 6-7.
Heading into week 15, the Rams have a 34.5% chance of making the playoffs and a 32.3% chance of winning the division. They rank 14th in our NFL power rankings. Their O/U record is 7-6, with their games averaging 48.5 points compared to a 47.2-point line.
Heading into week 15, the Rams are 11th in our offensive power rankings. They are 14th in the NFL in scoring, averaging 22.9 points per game, and sit 15th in yards per game with 340.7. In the passing game, they rank 12th in attempts and 9th in passing yards per game, averaging 237.7. On the ground, they are 21st in rushing attempts and 25th in rushing yards, with 103 per game. They rank 20th in 3rd-down conversions and 23rd in red zone conversion percentage, despite being 5th in red zone attempts. The Rams have struggled early in games, ranking 24th in 1st-quarter scoring.
Matthew Stafford has been on fire, posting a passer rating of 132 in week 14, with 320 yards and 2 touchdowns on 23/30 passing. He wasn’t sacked after being sacked twice in week 13 and five times in week 12. Puka Nacua led the Rams with 12 catches for 162 yards and a touchdown, while Kyren Williams had 87 rushing yards and 2 touchdowns on 29 carries. The Rams scored 6 points in the 4th quarter after putting up 14 in the 3rd and 17 in the 2nd. They converted 11 of 15 3rd downs and went 5/6 in the red zone.
In their 44-42 win over the Bills, the Rams’ defense gave up 342 yards through the air, with Buffalo averaging 9.2 yards per passing attempt. Despite their defensive struggles, the Rams’ offense was able to pull out the win. The Rams also struggled to stop the run, as Buffalo ran for 103 yards on just 17 attempts, averaging 6.1 yards per attempt. Los Angeles didn’t manage to record any sacks in the game and lost the tackles for loss battle by -4.
The Rams allowed Buffalo to convert on 55.6% of their third down attempts and gave up three passing touchdowns while holding the Bills to a 59.5% completion percentage. Even though the Rams gave up 445 total yards, they still came out on top in a high-scoring affair.
Will The 49ers Win At Home Over The Rams?
After three straight losses, the 49ers got back in the win column in week 14, easily taking care of the Bears 38-13. San Francisco entered the game as 3-point favorites and had no trouble covering the spread, with the teams combining for 51 points to hit the over. The win puts the 49ers at 6-7, leaving them 11th in the NFC and 4th in the NFC West with a 1-3 division record.
Heading into week 15, our power rankings have the 49ers 8th in the NFL, and they have a 10.7% chance of making the playoffs. Against the spread, San Francisco is 5-8, with an average scoring margin of 0 points per game. Their O/U record is 7-6, with their games averaging 47.4 points per game.
After struggling in weeks 12 and 13, the 49ers bounced back in week 14 with a 38-13 win over the Bears. Brock Purdy threw for 325 yards and 2 touchdowns, completing 20 of 25 passes. San Francisco scored 14 points in both the first and fourth quarters and converted 6 of 12 third downs. They also scored on 5 of 6 red zone trips.
Heading into week 15, the 49ers rank 12th in our offensive power rankings. They are 11th in the NFL in scoring, averaging 23.7 points per game, and 4th in total yards with 378.5 per game. Despite ranking 27th in pass attempts, they are 7th in passing yards, averaging 239.6 per game.
Even though the 49ers’ defense allowed two passing touchdowns in their 38-13 win over the Bears, they were still very effective. Chicago finished with just 94 yards through the air on 18 completions. San Francisco’s defense was dominant up front, recording seven sacks and holding the Bears to just 68 yards rushing on 21 attempts.
The 49ers’ pass rush was relentless, coming out on top in the QB hit differential by +4 and generating seven sacks. Despite the two passing touchdowns, Chicago struggled to move the ball through the air, finishing with a 75% completion rate on their passes.