Los Angeles Rams vs Arizona Cardinals Betting Pick & Prediction for 12/7

NFL Game preview

In Week 14 of the 2025 NFL season, the Los Angeles Rams visit the Arizona Cardinals at State Farm Stadium. The game is set for Sunday, December 7, with kickoff at 4:25 PM. Fans can catch the action on FOX.

The Rams come into this game with a strong 9-3 record, while the Cardinals are 3-9. The Rams have a slight edge in their road performance with a 4-2 record. In contrast, the Cardinals have struggled at home, holding a 1-5 record. This NFC West matchup will unfold under clear skies, with the retractable roof ensuring no wind affects the game.

Los Angeles Rams Team Preview

The Los Angeles Rams are coming off a close loss to the Carolina Panthers, 31-28. In that game, the Rams had 22 first downs and 227 passing yards. Matthew Stafford threw for 243 yards with two touchdowns but also had two interceptions.

In a recent home game, the Rams beat the Tampa Bay Buccaneers 34-7. Stafford was efficient, throwing for 273 yards and three touchdowns. The Rams defense was solid, allowing only 70 passing yards and grabbing two interceptions.

The Rams have some injury concerns with key players like Davante Adams and Kyren Williams listed as questionable. Despite these challenges, the team has shown strong offensive capabilities. Stafford is leading the offense with over 3,000 passing yards and 32 touchdowns this season.

Rams vs Cardinals Game Day Info

  • Sport: NFL
  • Teams: Los Angeles Rams vs. Arizona Cardinals
  • Venue: State Farm Stadium in Glendale, AZ
  • Date: Sunday, December 7, 2025
  • Betting Odds: Rams Moneyline -418, Cardinals Moneyline +326, Rams Spread -8.0 (-109), Cardinals Spread +8.0 (-110), Total Over 48.0 (-110), Total Under 48.0 (-109)

Arizona Cardinals Team Preview

The Arizona Cardinals have struggled in recent games. They lost to the Tampa Bay Buccaneers 20-17. The Cardinals had more passing yards with 291 compared to the Buccaneers’ 184, but they still came up short.

Jacoby Brissett leads the team at quarterback with 2,188 passing yards this season. He has thrown 13 touchdowns and 4 interceptions. Trey McBride is a key player with 88 receptions and 879 receiving yards.

The Cardinals are dealing with many injuries. Key players like Kyler Murray and James Conner are out. This could make it harder for them to turn their season around.

BTB Betting Pick

The Rams are favored by 8 points against the Cardinals. The Rams have a strong passing attack, ranked 10th, while the Cardinals’ defense is 21st in opponent offensive yards. The Cardinals’ offense scores well, ranking 12th, which could keep the game close. Pick the Cardinals to cover the spread at +8.0.

The total for the game is set at 48 points. The Rams’ defense allows a lot of yards, ranked 26th, and the Cardinals’ offense is efficient on third downs, ranked 8th. This could lead to a high-scoring game. Take the over at 48.0 points.