Lipscomb Bisons vs Duke Blue Devils NCAAB Betting Pick & Prediction for 12/16

The Lipscomb Bisons will travel to Cameron Indoor Stadium to play against the Duke Blue Devils on Tuesday, December 16, 2025. The game is scheduled to start at 6:00 PM ET and will be broadcast on ACCN. This non-conference matchup features the Bisons from the Atlantic Sun Conference taking on the third-ranked Blue Devils from the Atlantic Coast Conference.

Duke enters the game with an impressive 10-0 record, including a 6-0 mark at home. Meanwhile, Lipscomb stands at 6-4 for the season, having struggled on the road with a 2-4 record. The spread favors Duke heavily, giving them a -33.5 advantage, while the over/under is set at 150.5 points.

Lipscomb Bisons vs Duke Blue Devils Game Day Info

  • Sport: College Basketball
  • Teams: Lipscomb Bisons vs Duke Blue Devils
  • Venue: Cameron Indoor Stadium, Durham NC
  • Date: Tuesday, December 16, 2025
  • Betting Odds: Lipscomb Spread +33.5 (-111), Duke Spread -33.5 (-112), Over/Under 150.5

Lipscomb Bisons Team Preview

The Lipscomb Bisons have had a solid start to their season with a 6-4 record. They have been strong at home with a 4-0 record but have struggled on the road, going 2-4. In their recent games, they have shown strong offensive skills, scoring 92 points in their last game against Alabama A&M.

Key players for the Bisons include Grant Asman and Mateo Esmeraldo. Asman has been consistent, averaging 13.4 points and 6.4 rebounds per game. Esmeraldo contributes with 10.4 points and leads the team in assists with 66 total this season.

The Bisons’ offense relies heavily on three-point shooting, making 10.9 per game. Their field goal percentage sits at 44.4%, ranking them 240th. On defense, they average 8.6 steals per game, showing their ability to apply pressure on opponents.

Duke Blue Devils Team Preview

The Duke Blue Devils have been strong this season. They hold a 10-0 record and are ranked #3 in the AP rankings. Their performance at home is perfect with a 6-0 record.

The Blue Devils are scoring an average of 86.8 points per game. They have an effective field goal percentage of 58.4%, ranking them 19th. Their 2-point shooting is at 63.1%, placing them 9th in the nation.

Cameron Boozer is leading the team with 23.0 points and 9.9 rebounds per game. Caleb Foster contributes with 9.2 points and 3.5 rebounds. The team has a solid 42.2 total rebounds per game, which ranks 26th overall.

BTB Betting Pick

For the spread, picking Lipscomb +33.5 (-111) seems reasonable. Duke scores 86.8 points per game, while Lipscomb scores 80.4. The projected score is Duke 86, Lipscomb 80, which suggests that the spread is too large. Lipscomb’s ability to make 10.9 three-pointers per game can help them keep the game closer than expected.

For the over/under, the recommendation is to pick the over 150.5 (-115). The combined points per game for both teams is 167.2, which is well above the line. Both teams have high offensive stats, with Duke’s effective field goal percentage at 58.4% and Lipscomb’s three-point shooting ranking 31st. This indicates a high-scoring game is likely.