Detroit Pistons vs New York Knicks Betting Pick & Prediction 4/21/25

The Detroit Pistons travel to Madison Square Garden to take on the New York Knicks in an Eastern Conference matchup. The Knicks are favored by 6.5 points and have won two straight games, while the Pistons have lost three straight.

This game will tip off at 7:30 ET and can be seen on TNT. The over/under line for the game is 221.

DETROIT PISTONS VS NEW YORK KNICKS BETTING PICK

The Pick: New York Knicks -6.5

This game will be played at Madison Square Garden at 7:30 ET on Monday, April 21st.

WHY BET THE NEW YORK KNICKS:

  • We have this one finishing with a projected score of 168-140 in favor of the Knicks.
  • Our projections have Jalen Brunson finishing with 28 points, 3 rebounds and 8 assists.
  • From the field, we have the Knicks finishing with a field goal percentage of 47.4% and knocking down 18 threes.

Will the Pistons Come Through as Road Underdogs?

Detroit’s season record fell to 44-38 after a 123-112 road loss to the Knicks on Saturday. The Pistons entered the game as +7 point underdogs and failed to cover the spread. The total score of 235 points exceeded the pre-game O/U line of 221.5 by 13.5 points.

After a 36-26 third quarter, Detroit led 91-83 heading into the 4th. However, the Knicks went on a 21-0 run, turning a 98-92 deficit into a 113-98 lead, and outscored the Pistons 40-21 in the final period.

Tobias Harris led the Pistons with 25 points and 6 rebounds, hitting 4 threes at 80% in their 123-112 loss to the Knicks. Cade Cunningham added 21 points and 12 assists, despite shooting just 38.1%, while Malik Beasley contributed 20 points, making 6 threes at 50% efficiency.

As a team, the Pistons shot 46.9% from beyond the arc, connecting on 15 threes, and finished with an overall field goal percentage of 47.7%. Harris scored 13 points in the 2nd quarter, while Tim Hardaway added 12 of his 19 points in the 3rd.

The Pistons gave up 123 points to the Knicks on Saturday, with a particularly tough 4th quarter where they allowed 40 points. Detroit’s defense allowed New York to shoot 52% from the field.

From beyond the arc, the Pistons allowed 10 threes on 38% shooting. The Knicks also went 15/17 from the free-throw line. Detroit finished with 26 defensive rebounds, 6 steals, and 9 blocks.

Will the Knicks Live Up to Expectations at Home?

The Knicks improved to 51-31 after a 123-112 win over the Pistons on Saturday. Playing at home, New York entered the game as 7-point favorites and covered the spread. The total score of 235 points exceeded the over/under line of 221.5 by 13.5 points.

New York and Detroit were tied at 27 after the 1st quarter, and the Knicks held a slight edge after the 2nd, leading 57-55. However, the Pistons took control in the 3rd, outscoring the Knicks 36-26. New York responded in the 4th, going on a 21-0 run to turn a 98-92 deficit into a 113-98 lead, while holding the Pistons to 21 points in the quarter.

Jalen Brunson led the Knicks to a 123-112 win over the Pistons, scoring 34 points and dishing out 8 assists. Brunson scored 11 points in the 3rd quarter and added 12 more in the 4th. Karl-Anthony Towns and OG Anunoby each contributed 23 points, with Towns shooting 71.4% from the field.

The Knicks shot 52.7% as a team, hitting 10 threes at a 38.5% rate. Anunoby made 3 threes, shooting 37.5% from deep. Cameron Payne added 11 of his 14 points in the 4th quarter, while Josh Hart scored 8 of his 13 points in the final period.

Despite giving up 36 points in the 3rd quarter, the Knicks tightened up defensively in the 4th, allowing just 21 points to secure the win over the Pistons. Overall, they gave up 112 points on 47% shooting.

New York struggled to defend the three, with Detroit hitting 15 threes at a 46% clip. The Knicks sent the Pistons to the line 20 times, where they made 15 free throws. Defensively, the Knicks recorded 12 steals and 9 blocks.