Denver Nuggets vs Portland Trail Blazers Betting Pick & Prediction 3/21/25

At 10:00 ET, the Portland Trail Blazers (-119) will host the Denver Nuggets (-101) in a Western Northwest division matchup. The Trail Blazers are favored by 1 point, and the over/under line is set at 225.5.
Portland is currently on a 3-game winning streak and is 12th in the Western Conference with a record of 31-39. The Nuggets are 3rd in the West at 44-26.
DENVER NUGGETS VS PORTLAND TRAIL BLAZERS BETTING PICK
The Pick: Portland Trail Blazers -1
This game will be played at Moda Center at 10:00 ET on Friday, March 21st.
WHY BET THE PORTLAND TRAIL BLAZERS:
- We have this one finishing with a projected score of 116-99 in favor of the Trail Blazers.
- Our projections have Anfernee Simons finishing with 20 points, 3 rebounds and 5 assists.
- From the field, we have the Trail Blazers finishing with a field goal percentage of 43.3% and knocking down 14 threes.
Will Denver Be The Talk of Moda Center?
Denver’s record fell to 44-26 after a 120-108 road loss to the Lakers on Wednesday. The Nuggets entered the game as +5.5 point underdogs and failed to cover the spread. The total score of 228 points went over the pre-game line of 224.5.
The Lakers took control early with a 12-0 run, extending their lead from 24-16 to 36-16. Denver outscored the Lakers 31-15 in the 4th quarter, but it was too late to overcome the deficit.
Aaron Gordon led the Nuggets with 26 points and 11 rebounds in their 120-108 loss to the Lakers, hitting 5 threes at a 55.6% clip. Jalen Pickett added 14 points, knocking down 4 threes at 66.7% from deep.
Denver made 13 threes as a team, shooting 33.3% from beyond the arc and 47.1% overall. Gordon scored 10 points in the 3rd quarter, while Pickett added 12 in the 4th.
The Nuggets struggled defensively in the 1st quarter, giving up 46 points, but they tightened up in the 4th, allowing just 15. Overall, they allowed 120 points on 50% shooting from the Lakers.
From beyond the arc, Denver allowed 16 threes on 42% shooting. They sent the Lakers to the line 28 times, where they made 20 free throws. The Nuggets finished with 8 steals and 4 blocks.
Will Portland Win at Home?
Portland improved to 31-39 on the season with a 115-99 win over the Grizzlies on Wednesday. The Trail Blazers, who were +4.5 point underdogs, covered the spread with the win. The game’s total of 214 points fell well short of the 234.5-point O/U line.
Portland took control early, outscoring Memphis 38-29 in the 1st quarter and 33-29 in the 2nd. After the Grizzlies narrowed the gap by winning the 3rd quarter 31-25, the Trail Blazers clamped down defensively in the 4th, holding Memphis to just 10 points while going on an 11-0 run to seal the win.
Deni Avdija’s 31-point, 16-rebound performance, including 5 made threes at 62.5%, led the Trail Blazers to a win over the Grizzlies. Avdija scored 16 points in the 2nd quarter, and Portland hit 18 threes at 39.1% for the game.
Despite shooting just 41.7% overall, the Blazers’ three-point shooting was key, with Anfernee Simons adding 9 of his 22 points in the 4th quarter. Shaedon Sharpe contributed 17 points, hitting 3 threes.
Despite giving up 29 points in both the 1st and 2nd quarters and 31 in the 3rd, the Trail Blazers clamped down in the 4th, allowing just 10 points to secure the win. Overall, they held the Grizzlies to 99 points on 40% shooting.
Portland was especially effective at defending the three, limiting Memphis to 8 made threes on 26% shooting. The Grizzlies went 17/21 from the free-throw line. The Trail Blazers recorded 43 defensive rebounds, gave up 10 offensive boards, and added 6 blocks.