UTSA Roadrunners vs South Florida Bulls Betting Pick & Prediction for 11/6

In Week 11 of the 2025 season, the UTSA Roadrunners will travel to face the South Florida Bulls. The game is set to take place at Raymond James Stadium in Tampa, Florida. Fans can catch the action on ESPN at 7:30 PM on Thursday, November 6, 2025.
UTSA comes into the game with a 4-4 record, struggling on the road with only one win. South Florida, on the other hand, holds a 6-2 record and remains unbeaten at home. Both teams belong to the American Conference, adding an extra layer of competition to this matchup.
UTSA Team Preview
The UTSA Roadrunners recently showed strong offensive skills in their win against Tulane, scoring 48 points. The team had 391 passing yards and 144 rushing yards. They also had 28 first downs and made no interceptions in that game.
Owen McCown leads UTSA’s passing game with 1,675 yards and 17 touchdowns this season. Robert Henry Jr. is a key player in rushing, with 955 yards and nine touchdowns. Devin McCuin stands out in receiving with 43 receptions and six touchdowns.
UTSA’s defense has been effective in forcing turnovers, with seven interceptions this season. They are ranked eighth in interceptions and fumbles recovered. However, they have allowed 242 points, ranking them 117th in points against.
UTSA vs South Florida Game Day Info
- Sport: NCAA Football
- Teams: UTSA Roadrunners vs. South Florida Bulls
- Venue: Raymond James Stadium in Tampa, FL
- Date: Thursday, November 6, 2025
- Betting Odds: UTSA Moneyline +453, South Florida Moneyline -629, UTSA Spread +14.0 (-109), South Florida Spread -14.0 (-112), Total Over 68.5 (-111), Total Under 68.5 (-110)
South Florida Team Preview
The South Florida Bulls have had a mixed run this season. They narrowly lost to the Memphis Tigers 34-31, showing strong rushing with 295 yards. The Bulls also secured a win against Florida Atlantic Owls, dominating with a 48-13 score.
In their recent games, South Florida’s offense has been effective. They have scored 323 points, ranking 13th in the league. Their rushing game stands out, ranking 17th with 1806 yards this season.
The Bulls have several players dealing with injuries. Notably, Boogsie Silvera and Cartevious Norton are out for the season. Chas Nimrod and Alvon Isaac are questionable for upcoming games, which may impact their performance.
BTB Betting Pick
For the spread pick, take South Florida to cover the -14.0 spread against UTSA. South Florida has scored 323 points this season, ranking 13th, while UTSA has allowed 242 points, ranking 117th in defense. The projected score is South Florida 41, UTSA 24, suggesting South Florida covers the spread.
For the over/under pick, consider the under at 68.5 points. South Florida’s defense has allowed 195 points this season, ranking 86th, and UTSA’s offense has scored 272 points, ranking 35th. The projected total score is 65 points, which is below the set line of 68.5.