UNLV Runnin’ Rebels vs Wyoming Cowboys Betting Pick & Prediction for 10/4

In Week 6 of the 2025 regular season, the UNLV Runnin’ Rebels head to Laramie, Wyoming to take on the Wyoming Cowboys. This game will be held at the War Memorial Stadium, an outdoor field. Fans can catch the action on Saturday, October 4, 2025, at 7:00 PM on CBSS.
UNLV comes into this game with an impressive 4-0 record, with two wins on the road. They are yet to play a conference game this season. The Wyoming Cowboys have a 2-2 record, with one win and one loss at home. Both teams belong to the Mountain West Conference, making this matchup a key moment in their seasons.
UNLV Team Preview
The UNLV Runnin’ Rebels have shown strong performance in recent games. They scored a close win against Miami (OH) RedHawks, 41-38. In this game, they recorded 31 first downs and gained 220 rushing yards.
UNLV’s offense has been effective this season. They are ranked 37th in points for and 49th in rushing yards. Anthony Colandrea, their quarterback, has thrown for 940 yards and 8 touchdowns in four games.
On defense, UNLV has intercepted 8 passes, ranking 9th in this category. They have allowed 113 points, placing them 79th in points against. Despite the injury to QB Alex Orji, their offense remains productive.
UNLV vs Wyoming Game Day Info
- Sport: NCAA Football
- Teams: UNLV Runnin’ Rebels vs. Wyoming Cowboys
- Venue: War Memorial Stadium (WY) in Laramie, WY
- Date: Saturday, October 4, 2025
- Betting Odds: UNLV Moneyline -172, Wyoming Moneyline +143, UNLV Spread -3.5 (-110), Wyoming Spread +3.5 (-110), Total Over 49.5 (-112), Total Under 49.5 (-109)
Wyoming Team Preview
The Wyoming Cowboys have faced some tough games recently. They lost to Colorado 37-20 and to Utah 31-6. In these games, their defense struggled, giving up 304 passing yards to Colorado and 311 rushing yards to Utah.
In their first two games, Wyoming showed promise with wins against Northern Iowa and Akron. They beat Northern Iowa 31-7 and Akron 10-0. In these games, their defense held strong, allowing only 59 rushing yards against Northern Iowa and 92 against Akron.
Wyoming’s offense has been led by quarterback Kaden Anderson. He has thrown for 711 yards and five touchdowns this season. However, the team faces injury challenges, with key players like Caleb Robinson and Patrick Broadway II out for the season.
BTB Betting Pick
For the spread pick, take UNLV to cover -3.5 against Wyoming. UNLV has scored 147 points this season, ranking 37th in points for, while Wyoming has only scored 67 points, ranking 86th. The projected score is UNLV 28, Wyoming 17, suggesting UNLV will cover the spread.
For the over/under pick, go with the under 49.5 points. UNLV’s defense has allowed 113 points, ranking 79th, and Wyoming’s defense has allowed 75 points, ranking 45th. The projected total score is 45, indicating the game will likely stay under the set total.