UCLA Bruins vs USC Trojans Betting Pick & Prediction for 11/29

College Football Preview

The UCLA Bruins will take on the USC Trojans in Week 14 of the 2025 regular season. The game will be held at the Los Angeles Memorial Coliseum in Los Angeles, CA. Kickoff is set for 7:30 PM on Saturday, November 29, and will be broadcast on NBC.

UCLA enters the game with a 3-8 record, while USC boasts an 8-3 record. The Bruins have struggled on the road with a 1-4 record, whereas the Trojans remain undefeated at home with a 6-0 record. Both teams are part of the Big Ten Conference, adding extra weight to this game.

UCLA Team Preview

UCLA Bruins have had a tough season with recent losses. They faced Washington Huskies and lost 48-14. In that game, UCLA managed only 10 first downs and 150 passing yards.

Against Ohio State Buckeyes, the Bruins fell 48-10. UCLA struggled with only 8 first downs and 68 rushing yards. Their defense allowed 222 rushing yards from Ohio State.

Injuries are a concern for UCLA. Nico Iamaleava, their top quarterback, is questionable due to neck spasms. Several other players, including key receivers and linemen, are also uncertain for the upcoming game.

UCLA vs USC Game Day Info

  • Sport: NCAA Football
  • Teams: UCLA Bruins vs. USC Trojans
  • Venue: Los Angeles Memorial Coliseum in Los Angeles, CA
  • Date: Saturday, November 29, 2025
  • Betting Odds: UCLA Moneyline +989, USC Moneyline -1926, UCLA Spread +21.5 (-107), USC Spread -21.5 (-113), Total Over 59.5 (-109), Total Under 59.5 (-111)

USC Team Preview

The USC Trojans had a mixed performance in recent games. In their last outing, they faced the Oregon Ducks and lost 42-27. Despite passing for 330 yards, they struggled with their rushing game, managing only 61 yards.

The Trojans showed strength in their games at home. They defeated Iowa 26-21 and Northwestern 38-17. In these games, their passing and rushing stats were strong, with 254 and 309 passing yards respectively.

Jayden Maiava leads the Trojans with 3174 passing yards this season. Makai Lemon has been a key receiver with 1124 receiving yards. However, the team faces some injury challenges, including Eli Sanders, who is out for the season.

BTB Betting Pick

For the spread, take UCLA to cover the +21.5 points. While USC has a strong offense ranked 14th in points for, UCLA’s defense has shown some ability with a top-10 ranking in interceptions and fumbles recovered. The projected score is USC 38, UCLA 21, which keeps UCLA within the spread.

For the total, consider betting on the over 59.5 points. USC’s offense ranks high with 409 points this season, and their defense has allowed 259 points. With a projected total of 59 points, both teams could contribute enough to hit the over.