Toronto Blue Jays vs Los Angeles Angels Betting Pick & Prediction for 4/22

The Toronto Blue Jays visit the Los Angeles Angels for an MLB regular season game. The game is set for Wednesday, April 22, 2026, at Angel Stadium of Anaheim. The Blue Jays come in with a 9-13 record, while the Angels hold an 11-13 record.
Both teams have had similar performances in their last ten games, each going 4-6. The Blue Jays are on a two-game winning streak, while the Angels have lost their last three. Weather conditions are mild with scattered clouds and a calm wind. Eric Lauer will pitch for the Blue Jays, and José Soriano will start for the Angels.
Toronto Blue Jays Team Preview
The Toronto Blue Jays have had a mixed run in their recent games. They managed a win against the Los Angeles Angels with a score of 5-2, thanks to strong performances from Vladimir Guerrero Jr. and Dylan Cease. Guerrero Jr. went 3-for-4 with a home run, while Cease struck out 12 over five innings.
In their game against the Arizona Diamondbacks, the Blue Jays secured a 10-4 victory. Kevin Gausman pitched six solid innings, and the team collected 14 hits. Kazuma Okamoto and Nathan Lukes contributed significantly with extra-base hits.
The Blue Jays’ batting average ranks 5th in the league, while their pitching has room for improvement. Eric Lauer, with a 7.13 ERA this season, is set to start the next game. He will face José Soriano of the Angels, who has been exceptional with a 0.28 ERA.
Blue Jays vs Angels Game Day Info
- Sport: MLB
- Teams: Toronto Blue Jays vs. Los Angeles Angels
- Venue: Angel Stadium of Anaheim in Anaheim, CA
- Date: Wednesday, April 22, 2026
- Betting Odds: Blue Jays Moneyline +130, Angels Moneyline -156
Los Angeles Angels Team Preview
The Los Angeles Angels have had a mixed performance in their recent games. They lost to the Toronto Blue Jays on April 20th with a score of 5-2. Reid Detmers pitched for six innings, allowing four earned runs and one home run.
The Angels also faced the San Diego Padres, where they lost two games in a row. On April 19th, they lost 2-1 despite Walbert Urena striking out eight in six innings. The previous day, they were defeated 4-1 with Yusei Kikuchi allowing no earned runs over six innings.
In terms of batting, Zach Neto and Mike Trout are key contributors to the lineup. Neto holds a batting average of .247, while Trout has hit seven home runs this season. The Angels’ batting average ranks 20th, but they are second in home runs with 34 this season.
BTB Betting Pick
The Angels are favored with a moneyline of -156. The Blue Jays have a moneyline of +130. The Angels have a better batting average against and lower ERA, suggesting they might win. The projected score is Angels 5, Blue Jays 4. Our pick is the Angels to win straight up.
The total for the game is set at 8.5. The Blue Jays have a high strikeout rate, while the Angels have a solid pitching staff. This points to a lower-scoring game. Our pick is to take the under 8.5.