Tennessee Titans vs Indianapolis Colts Betting Pick & Prediction for 10/26

The Tennessee Titans are set to visit the Indianapolis Colts in a Week 8 game of the 2025 NFL season. The game will take place at Lucas Oil Stadium, known for its retractable roof, which may be closed due to overcast clouds and a light breeze. Fans can catch the action on CBS this Sunday, October 26, at 4:25 PM.

The Titans, with a current record of 1-6, are looking to turn their season around under interim head coach Mike McCoy. They face a tough challenge against the Colts, who hold a strong 6-1 record. The Colts have been perfect at home this season with a 4-0 record. This game is an AFC South division matchup, adding extra importance to the outcome for both teams.

Tennessee Titans Team Preview

The Tennessee Titans have been on a rough stretch lately, losing four of their last five games. Their most recent game was a loss to the New England Patriots, with a score of 31-13. The Titans struggled in the run game, managing only 39 rushing yards, while the Patriots rushed for 175 yards.

Quarterback Cameron Ward has been a key player for the Titans, throwing for 1,356 yards in the season so far. However, he has thrown more interceptions (5) than touchdowns (4), which has been a concern. Running back Tony Pollard leads the rushing attack with 380 yards but only has two rushing touchdowns this season.

The Titans have a few injury concerns heading into their next game. Wide receiver Calvin Ridley is questionable with a hamstring injury, and defensive tackle Jeffery Simmons is also questionable. The team will need these players healthy to help turn their season around.

Titans vs Colts Game Day Info

• Sport: NFL
• Teams: Tennessee Titans vs. Indianapolis Colts
• Venue: Lucas Oil Stadium in Indianapolis, IN
• Date: Sunday, October 26, 2025
• Betting Odds: Titans Moneyline +748, Colts Moneyline -1210, Titans Spread +14.0 (-110), Colts Spread -14.0 (-110), Total Over 47.0 (-111), Total Under 47.0 (-109)

Indianapolis Colts Team Preview

The Indianapolis Colts have had a strong start to their 2025 season. They have secured four wins in their last five games, including a 38-24 victory over the Los Angeles Chargers. The team shows a balanced attack with both a solid passing and rushing game.

Jonathan Taylor has been a standout player for the Colts. He leads the league in rushing yards with 697 and has scored 10 touchdowns. Daniel Jones, the quarterback, has also been effective, ranking first on the team with 1,790 passing yards and 10 touchdowns.

The Colts face some challenges with injuries. Key players like Anthony Richardson Sr. and Spencer Shrader are on the injured reserve list. Despite this, the team continues to perform well, showing depth and strength in their lineup.

BTB Betting Pick

The Titans are getting +14.0 points against the Colts. The Titans have struggled offensively, ranking 25th in scoring, but their defense is strong in interceptions, ranked 9th. The Colts’ defense ranks 23rd in opponent scoring, making the Titans a good pick to cover the spread. Projected score: Colts 28, Titans 17.

The total for this game is set at 47.0. The Titans and Colts both have defenses that give up points, ranked 27th and 23rd, respectively. However, their offensive outputs suggest a lower-scoring game. The under is the safer bet here. Projected total: 45 points.