TCU Horned Frogs vs Houston Cougars Betting Pick & Prediction for 11/22

College Football Preview

Week 13 of the 2025 NCAA football season brings an exciting game between the TCU Horned Frogs and the Houston Cougars. The game is set to take place at TDECU Stadium in Houston, Texas. Fans can tune in on FOX at 4:00 PM on Saturday, November 22.

TCU enters the game with a 6-4 record, holding a 2-3 record on the road. Houston has an 8-2 record and is ranked #25 in the AP poll. The Cougars have a 3-2 home record and are ranked #24 in the Coaches Poll.

TCU Team Preview

TCU Horned Frogs have shown mixed results in recent games. They experienced a tough loss against BYU, with a score of 44-13. In that game, TCU recorded 183 passing yards and 115 rushing yards but had two interceptions.

In their game against Iowa State, TCU came close but lost 20-17. They managed 319 passing yards and 113 rushing yards. However, three fumbles and two interceptions affected their chances.

TCU had a strong game against West Virginia, winning 23-17. They secured 247 passing yards and 107 rushing yards. The team capitalized on three fumbles by West Virginia to secure the win.

TCU vs Houston Game Day Info

  • Sport: NCAA Football
  • Teams: TCU Horned Frogs vs. Houston Cougars
  • Venue: TDECU Stadium in Houston, TX
  • Date: Saturday, November 22, 2025
  • Betting Odds: TCU Moneyline -104, Houston Moneyline -117, TCU Spread +1.5 (-115), Houston Spread -1.5 (-106), Total Over 54.5 (-115), Total Under 54.5 (-106)

Houston Team Preview

The Houston Cougars have had a mixed season with some wins and losses. In their recent game against the UCF Knights, they won 30-27. The team showed strong performance with 223 passing yards and 215 rushing yards.

Earlier in the season, the Cougars faced the West Virginia Mountaineers and lost 45-35. In that game, they recorded 318 passing yards but struggled with five fumbles. Despite the loss, they had more first downs than their opponents.

The Cougars’ top quarterback, Conner Weigman, has played in 10 games with 2,113 passing yards. Dean Connors leads the running backs with 725 rushing yards. Amare Thomas is the top wide receiver with 737 receiving yards and eight touchdowns.

BTB Betting Pick

For the spread pick, take Houston to cover -1.5 (-106) against TCU. TCU has struggled defensively this season, allowing 265 points and ranking 103rd in points against. Houston’s defense has been slightly better, ranking 81st with 221 points allowed. The projected score is Houston 28, TCU 26.

For the over/under pick, choose the under 54.5 (-106). Both teams have had moderate offensive outputs, with TCU scoring 307 points and Houston 295 points this season. With both teams having strong defensive rankings in interceptions and sacks, the total points are likely to stay under. The projected total is 54 points.