St. Louis Cardinals vs Milwaukee Brewers Betting Pick & Prediction for 5/25

The St. Louis Cardinals and Milwaukee Brewers meet for an MLB regular season game. The Brewers play at home with a record of 30-20. They are first in the NL Central and come off a two-game losing streak. The Cardinals, with a 29-22 record, are second in the division. They have lost one game in a row. The game will be at American Family Field in Milwaukee, Wisconsin.
Matthew Liberatore will pitch for the Cardinals. He has a 2-2 record and a 4.70 ERA this season. The Brewers will have Jacob Misiorowski on the mound. He has a 4-2 record and a 1.89 ERA. The game is set for the afternoon of May 25, 2026, at 2:10 PM. Fans can watch it on the BREW channel. The weather is expected to be clear, but the retractable roof might limit wind impact.
St. Louis Cardinals Team Preview
The St. Louis Cardinals recently played a series of games with mixed results. They secured a strong win against the Cincinnati Reds, winning 8-1. In that game, Andre Pallante pitched effectively, allowing only 1 earned run over 6 innings. The Cardinals’ offense was fueled by home runs from Bryan Torres and Jordan Walker.
In another game against the Reds, the Cardinals fell short, losing 7-6. Jordan Walker stood out with 3 hits and 4 RBIs. Despite the loss, the team’s batting lineup showed power with 2 home runs, one each from Walker and José Fermín.
On the season, the Cardinals’ batting average ranks 9th in the league at .242. Their pitching has faced challenges, with an ERA of 4.20, placing them 21st. Matthew Liberatore will start in the next game against the Brewers, aiming to improve his 4.70 ERA.
Cardinals vs Brewers Game Day Info
- Sport: MLB
- Teams: St. Louis Cardinals vs. Milwaukee Brewers
- Venue: American Family Field in Milwaukee, WI
- Date: Monday, May 25, 2026
- Betting Odds: Cardinals Moneyline +181, Brewers Moneyline -217, Cardinals Runline +1.5 (-117), Brewers Runline -1.5 (-104), Total Over 7.5 (-115), Total Under 7.5 (-105)
Milwaukee Brewers Team Preview
The Milwaukee Brewers have had a mixed performance in their recent games. They secured a win against the Los Angeles Dodgers on May 22nd, with a score of 5-1. Logan Henderson was strong on the mound, allowing no earned runs over five innings.
In the last two games against the Dodgers, the Brewers struggled. They lost 11-3 and 5-1, with starting pitchers Robert Gasser and Brandon Sproat facing difficulties. The team had limited offensive output, with no home runs in these games.
Offensively, the Brewers’ season stats show a batting average of .246, ranking 6th. They have been successful on the bases, ranking 2nd in stolen bases. Their pitching staff has an ERA of 3.31, which is 4th in the league, showing strength in their rotation.
BTB Betting Pick
The Brewers are favored to win with a moneyline of -217. Their strong pitching, with a 3.31 ERA ranking 4th, gives them an edge. The Cardinals have a moneyline of +181, but their pitching ranks lower with a 4.20 ERA at 21st. Our pick is for the Brewers to win the game.
The total for this game is set at 7.5 runs. The Brewers’ pitching has been solid, allowing a batting average against of .219, ranking 3rd. The Cardinals’ hitting ranks 9th in batting average at .242. We project the score to stay under 7.5 runs, making the under (-105) our recommended pick.