Siena Saints vs Duke Blue Devils NCAAB Betting Pick & Prediction for 3/19

The Siena Saints will meet the Duke Blue Devils in the NCAA Men’s Division I Basketball Tournament. This first-round game in the East Region takes place at Bon Secours Wellness Arena in Greenville, SC. Fans can watch the game on CBS at 2:50 PM ET on Thursday, March 19, 2026. Siena enters as the 16 seed with a 23-11 record in the Metro Atlantic Athletic Conference. They face top-seeded Duke, who finished the regular season at 32-2 in the Atlantic Coast Conference. Duke holds the number one AP rank and looks to repeat last year’s success in the tournament.

Siena Saints vs Duke Blue Devils Game Day Info

  • Sport: College Basketball
  • Teams: Siena Saints vs Duke Blue Devils
  • Venue: Bon Secours Wellness Arena, Greenville SC
  • Date: Thursday, March 19, 2026
  • Betting Odds:
    • Siena Spread: +28.5
    • Duke Spread: -28.5
    • Siena MoneyLine: +4500
    • Duke MoneyLine: -41125
    • Over/Under: 135.5
    • Favorite: Duke
    • Underdog: Siena

Siena Saints Team Preview

The Siena Saints have been doing well in their recent games. They won their last game against Merrimack College Warriors by 10 points, scoring 64 points. Gavin Doty led the team with 23 points, 8 rebounds, and 2 assists.

In the game against Fairfield Stags, the Saints secured a win by 15 points with a score of 76-61. Justice Shoats scored 26 points, while Gavin Doty added 25 points. The team had a field goal percentage of 46.2% in that game.

The Saints also defeated Mount St. Mary’s Mountaineers with a score of 63-58. Brendan Coyle was a key player with 17 points and 9 rebounds. Overall, the Saints have shown strong performances in their recent games.

Duke Blue Devils Team Preview

The Duke Blue Devils have had a strong season with a 32-2 overall record. In their recent games, they secured victories over Virginia, Clemson, and Florida State. Against Virginia, they won 74-70, showing solid performance from players like Isaiah Evans and Cayden Boozer.

Duke’s offensive stats are impressive, with an average of 82.3 points per game. They rank 24th in field goal percentage at 49.0%. Despite a slower pace with 65.7 possessions per game, they maintain efficient scoring.

Key players for Duke include Cameron Boozer and Isaiah Evans. Cameron Boozer leads in scoring, averaging 22.5 points per game, while Isaiah Evans contributes 14.9 points per game. Their rebounding and assist numbers further strengthen the team’s performance.

BTB Betting Pick

Duke is favored by 28.5 points against Siena. Duke averages 82.3 points per game, while Siena scores 70.5 points per game. With Duke’s strong offense and Siena’s lower scoring, Duke is likely to cover the spread. The projected score is Duke 85, Siena 55.

The over/under line is set at 135.5 points. Duke’s offense is efficient, but Siena’s slower pace could limit scoring. With a projected total of 140 points, the over is a reasonable pick. The game might see Duke scoring heavily, pushing the total over the line.