San Diego Padres vs Seattle Mariners Betting Pick & Prediction for 5/16

The San Diego Padres visit the Seattle Mariners for a night game at T-Mobile Park. The Padres have a record of 26-18 and are ranked second in the NL West. They recently won their last game and have a 6-4 record in their last ten games.
The Mariners have a 22-24 record and sit in third place in the AL West. They lost their last game and have a 5-5 record in their last ten games. The game will feature Walker Buehler for the Padres and Logan Gilbert for the Mariners as the probable starting pitchers.
San Diego Padres Team Preview
The San Diego Padres are preparing for their next game against the Seattle Mariners. Recently, they secured a 2-0 win against the Mariners, showing strong pitching. Randy Vásquez led the way with six scoreless innings and three strikeouts.
In their last five games, the Padres have had mixed results. They won three and lost two, with notable performances from players like Gavin Sheets and Miguel Andujar. Sheets had a home run in their 3-1 victory over the Brewers, while Andujar contributed with a home run and two RBIs in a 6-4 loss.
Offensively, the Padres are ranked 22nd in batting average this season, hitting .223. Xander Bogaerts leads the team with a .263 average and seven home runs. On the mound, Walker Buehler is set to start the next game, carrying a 5.20 ERA into the matchup.
Padres vs Mariners Game Day Info
- Sport: MLB
- Teams: San Diego Padres vs. Seattle Mariners
- Venue: T-Mobile Park in Seattle, WA
- Date: Saturday, May 16, 2026
- Betting Odds: Padres Moneyline +136, Mariners Moneyline -162
Seattle Mariners Team Preview
The Seattle Mariners have had a mixed bag of results in their recent games. They recently lost to the San Diego Padres with a score of 2-0. In this game, Emerson Hancock pitched six innings, allowing just one earned run and striking out six batters.
In a game against the Houston Astros on May 14, the Mariners won by five runs. They managed to collect 11 hits, including two home runs. Luis Castillo started the game, going 5 2/3 innings and giving up three earned runs.
The Mariners’ batting lineup has players like Julio Rodríguez and Randy Arozarena, who have been contributing to the team’s offense. Rodríguez has a batting average of .257 with seven home runs. Arozarena is hitting .305 and has four home runs so far this season.
BTB Betting Pick
The Mariners are favored to win with a moneyline of -162. The Padres have a moneyline of +136. Based on the Mariners’ better pitching stats, with a 3.58 ERA ranked 6th, the pick is for the Mariners to win. The projected score is Mariners 4, Padres 3.
The total for the game is set at 7.0 runs. Both teams have solid pitching, with the Padres holding a 4.04 ERA and the Mariners at 3.58. Given these figures, the recommendation is to take the under 7.0 runs. The projected total is 7 runs, suggesting a close game to the line.