San Antonio Spurs vs Dallas Mavericks Betting Pick & Prediction for 10/22
This article was published on Oct 22, 2025. Today’s picks NBA picks

The NBA regular season is set to begin with an exciting game between the San Antonio Spurs and the Dallas Mavericks. Both teams are starting the season with a clean slate, holding a 0-0 record. The game will take place at the American Airlines Center on Wednesday, October 22, 2025, at 9:30 PM. Fans can catch the action live on ESPN.
The Spurs, led by Head Coach Mitch Johnson, had a strong preseason with a 4-0 record. They will aim to carry that momentum into the regular season. On the other side, the Mavericks, coached by Jason Kidd, also had a successful preseason, finishing with a 3-1 record. The game will be a test for both teams as they look to start the season on a high note.
Spurs vs Mavericks Game Day Info
- Sport: NBA
- Teams: San Antonio Spurs vs. Dallas Mavericks
- Venue: American Airlines Center
- Date: Wednesday, October 22, 2025
- Betting Odds:
- Spurs Spread: -2.5 (-110)
- Mavericks Spread: +2.5 (-110)
- Spurs MoneyLine: +118
- Mavericks MoneyLine: -139
- Over/Under: 225.5
San Antonio Spurs Team Preview
In recent games, the San Antonio Spurs have shown strong performances. They secured a win against the Indiana Pacers, scoring 133 points while holding the Pacers to 104. Victor Wembanyama and Stephon Castle were standout players, with Wembanyama grabbing 12 rebounds and Castle dishing out 9 assists.
Victor Wembanyama has been a key player for the Spurs. Last regular season, he averaged 24.3 points and 11 rebounds per game. His recent games have continued this trend, scoring 27 points and grabbing 11 rebounds in one game against the Pacers.
Currently, the Spurs are dealing with some injuries. De’Aaron Fox is out with a hamstring issue, and Kelly Olynyk is recovering from heel surgery. Despite these setbacks, the team has managed to perform well in recent games.
Dallas Mavericks Team Preview
The Dallas Mavericks recently played three preseason games. They won against the Los Angeles Lakers, 121-94, with a strong shooting percentage of 50.6%. In another game, they secured a 114-101 win over the Utah Jazz, though their shooting was lower at 39.4%. However, they faced a loss against the Charlotte Hornets, 120-116, despite shooting 51.1%.
Anthony Davis is a key player for the Mavericks. Last season, he averaged 24.7 points, 11.6 rebounds, and 3.5 assists per game. Dereck Lively II and P.J. Washington also had notable performances in the recent games, contributing points and rebounds.
The Mavericks have some injury concerns as the new season approaches. Kyrie Irving is out with a torn left ACL and will miss the start of the season. Dante Exum is also out due to knee irritation, while Daniel Gafford is doubtful with an ankle sprain.
BTB Betting Pick
The Mavericks are favored by 2.5 points against the Spurs. With the Mavericks having the edge in the odds, taking them to cover the spread at -2.5 seems reasonable. The projected score for this game is not available, but given the odds, the Mavericks are likely to win by more than 2.5 points.
The over/under for the game is set at 225.5 points. Without specific scoring data, it’s challenging to predict the exact total. However, considering the line, betting on the under at 225.5 could be a safer choice due to the slight lean in odds toward the under at -112.