Purdue Boilermakers vs Michigan Wolverines Betting Pick & Prediction for 11/1

Week 10 of the 2025 regular season brings the Purdue Boilermakers to Ann Arbor to face the Michigan Wolverines. The game will be held at Michigan Stadium, an outdoor field, on Saturday, November 1, 2025, at 7:00 PM. Fans can catch the action on BTN.
Purdue, with a 2-6 record, has struggled on the road, holding a 0-3 away record. In contrast, Michigan has a solid 6-2 record, remaining unbeaten at home with a 4-0 record. Both teams are part of the Big Ten conference, adding extra importance to this game.
Purdue Team Preview
The Purdue Boilermakers have faced a tough stretch recently. In their latest game, they fell to the Rutgers Scarlet Knights, 27-24. Purdue’s offense had 14 first downs and 218 rushing yards in that game.
Looking at their previous outing, Purdue struggled against the Northwestern Wildcats, losing 19-0. They managed only 11 first downs and had two fumbles. Their passing game gained 218 yards, but it was not enough to put points on the board.
In the game before that, the Boilermakers faced the Minnesota Golden Gophers and lost 27-20. Purdue had a strong rushing attack with 253 yards and 25 first downs. However, three interceptions hurt their chances to win.
Purdue vs Michigan Game Day Info
- Sport: NCAA Football
- Teams: Purdue Boilermakers vs. Michigan Wolverines
- Venue: Michigan Stadium, Ann Arbor, MI
- Date: Saturday, November 1, 2025
- Betting Odds: Purdue +962, Michigan -1798, Spread: Purdue +21.0 (-112), Michigan -21.0 (-108), Total: Over 49.5 (-110), Under 49.5 (-111)
Michigan Team Preview
The Michigan Wolverines have been strong on the ground this season. They rank 12th in rushing yards with 1,794 yards. Their recent game against the Michigan State Spartans showed their running strength with 294 rushing yards.
Quarterback Bryce Underwood has been solid, throwing for 1,526 yards across eight games. He has seven passing touchdowns and only two interceptions. The team’s passing attack is ranked 93rd, but they have been effective when needed.
The Wolverines’ defense has been tough, allowing 139 points, ranking 64th in points against. They excel at pressuring quarterbacks, with 22 sacks, ranking 9th. Their defense also has 11 interceptions, showing their ability to create turnovers.
BTB Betting Pick
For the spread pick, taking Michigan to cover -21.0 (-108) is a strong choice. Michigan has scored 232 points this season, ranking 47th, while Purdue has allowed 222 points, ranking 113th. The projected score is Michigan 38, Purdue 14, which covers the spread.
For the over/under pick, the recommendation is to go with the under at 49.5 (-111). Purdue’s offense ranks 74th in points scored with 183, and Michigan’s defense ranks 64th, allowing 139 points. With a projected total of 52, the game is expected to go slightly over, but given the defensive ranks, the under is the safer bet.