Oklahoma State Cowboys vs Iowa State Cyclones NCAAB Betting Pick & Prediction for 1/10

The Oklahoma State Cowboys are set to play the Iowa State Cyclones on Saturday at Hilton Coliseum. This Big 12 conference game will be broadcast on ESPN2 at 4:00 PM ET. The Cowboys come into this game with a record of 13-2 and an away record of 2-2.
On the other side, the Cyclones are ranked #3 and have an impressive 15-0 record. They have not lost a home game this season, standing at 12-0. The betting odds show the Cyclones as the favorite with a spread of -18.5, while the Cowboys have a spread of +18.5.
Oklahoma State Cowboys vs Iowa State Cyclones Game Day Info
- Sport: College Basketball
- Teams: Oklahoma State Cowboys vs Iowa State Cyclones
- Venue: Hilton Coliseum, Ames IA
- Date: Saturday, January 10, 2026
- Betting Odds: Iowa State Cyclones -18.5 (-110), Oklahoma State Cowboys +18.5 (-110)
Oklahoma State Cowboys Team Preview
The Oklahoma State Cowboys have been strong this season with a 13-2 record. They have won 11 of their games at home, while their away record stands at 2-2. They recently defeated UCF Knights 87-76, displaying solid shooting with a field goal percentage of 47.2%.
Anthony Roy has been a key player for the Cowboys. He scored 22 points against Texas Tech and 27 points against Bethune-Cookman. His average points per game this season is 17.5, leading the team in scoring.
The Cowboys’ offense is effective, with an average of 90.2 points per game. They also excel in free throws, making 20.1 per game. Defensively, they have room for improvement, as they average 12.5 turnovers per game.
Iowa State Cyclones Team Preview
The Iowa State Cyclones are having an impressive season. They are ranked #3 in the AP poll and have a perfect record of 15-0. At home, the Cyclones are 12-0, showing strong performance on their own court.
Offensively, the Cyclones score 88.3 points per game. Their field goal percentage is high at 52.3%, which is 6th in the nation. They also make 9.1 three-pointers per game, hitting 41.3% of them, ranking 16th in the nation.
Joshua Jefferson is a key player for Iowa State, averaging 17.6 points and 7.9 rebounds per game. Milan Momcilovic also contributes significantly with 17.5 points per game. Tamin Lipsey adds 14.8 points and 5.6 assists per game, helping the team excel in both scoring and playmaking.
BTB Betting Pick
The spread for the game is Iowa State -18.5. Oklahoma State scores 90.2 points per game, while Iowa State scores 88.3 points per game. With both teams showing strong offensive numbers, Iowa State’s better defensive stats make them the pick to cover the spread. The projected score is Iowa State 95, Oklahoma State 75, favoring Iowa State to win by 20 points.
The over/under for the game is set at 164.5. Given Oklahoma State’s high-scoring average and Iowa State’s efficient shooting, the total is likely to go over. The projected combined score is 170, suggesting the over is the better pick. Both teams’ offensive strengths support this prediction.