Ohio State Buckeyes vs Illinois Fighting Illini Betting Pick & Prediction for 10/11

College Football Preview

The Ohio State Buckeyes head to Champaign for a Week 7 game against the Illinois Fighting Illini. The game takes place at Memorial Stadium on Saturday, October 11, 2025. Kickoff is set for 12:00 PM, and fans can catch the action on FOX.

Ohio State enters the game ranked #1 in both the AP and Coaches Polls. They hold a perfect 5-0 record this season. Meanwhile, Illinois stands at 5-1 and is ranked #17. Both teams compete in the Big Ten Conference, making this a key conference game.

Ohio State Team Preview

Ohio State Buckeyes have been strong this season. They have won all their games so far. Their latest win was against Minnesota, with a score of 42-3.

Quarterback Julian Sayin leads the Buckeyes with 1,313 passing yards. He has thrown 13 touchdowns in five games. The team’s rushing attack is also solid, with Bo Jackson gaining 360 yards.

On defense, the Buckeyes rank 4th in points against. They have given up only 25 points this season. The team has also recorded 14 sacks and two interceptions.

Ohio State vs Illinois Game Day Info

  • Sport: NCAA Football
  • Teams: Ohio State Buckeyes vs. Illinois Fighting Illini
  • Venue: Memorial Stadium (Champaign, IL)
  • Date: Saturday, October 11, 2025
  • Betting Odds: Ohio State Moneyline -664, Illinois Moneyline +473, Ohio State Spread -14.5 (-110), Illinois Spread +14.5 (-110), Total Over 50.5 (-108), Total Under 50.5 (-113)

Illinois Team Preview

Illinois Fighting Illini recently had a strong win against Purdue. They scored 43 points while allowing 27. Their passing game was strong with 390 yards, while they held Purdue to 302 yards.

In a close game against USC, Illinois won 34-32. They achieved 25 first downs and passed for 331 yards. Their defense intercepted one pass, helping them secure the win.

Illinois has a few injuries to manage. Luke Zardzin and Ayden Knapik are questionable for the next game. Grant Smith, JJ Hirdes, and others are out for the season.

BTB Betting Pick

Ohio State is favored by 14.5 points against Illinois. Ohio State’s defense ranks 4th in points against, while Illinois’ offense ranks 11th in points for. This suggests Ohio State can cover the spread. The projected score is Ohio State 35, Illinois 20.

The total for the game is set at 50.5 points. Ohio State’s defense has allowed only 25 points this season, while Illinois has scored 222 points. This indicates a lower-scoring game. The under 50.5 is a solid pick.