New York Yankees vs Houston Astros Betting Pick & Prediction for 4/25

The New York Yankees will visit the Houston Astros for an MLB regular season game. The Yankees have a strong record of 17-9 and are leading their division. They are on a winning streak of seven games and have gone 8-2 in their last ten games.
On the other side, the Astros have a record of 10-17 and rank fifth in their division. They have struggled recently, losing their last game and posting a 4-6 record over the last ten games. The game will take place at Daikin Park in Houston, Texas, with a weather forecast of scattered clouds and a light breeze. Ryan Weathers will pitch for the Yankees, while Mike Burrows will start for the Astros.
New York Yankees Team Preview
The New York Yankees have been on a strong run lately, winning their last five games. Their recent 12-4 win over the Houston Astros showcased their batting power with four home runs. Jazz Chisholm Jr. and Ben Rice have been key hitters, contributing significantly in these games.
Ryan Weathers will be starting on the mound for the Yankees. He has a 3.18 ERA this season, with 36 strikeouts. In his last outing against the Kansas City Royals, he pitched over seven innings without allowing a run.
The Yankees’ batting lineup features Aaron Judge and Ben Rice, both with nine home runs this season. Ben Rice leads the team with a .316 batting average. The team’s overall batting average is .229, but they rank second in home runs with 39.
Yankees vs Astros Game Day Info
- Sport: MLB
- Teams: New York Yankees vs. Houston Astros
- Venue: Daikin Park in Houston, TX
- Date: Saturday, April 25, 2026
- Betting Odds: Yankees Moneyline -152, Astros Moneyline +128, Yankees Runline -1.5 (+107), Astros Runline +1.5 (-129), Total Over 9.0 (-117), Total Under 9.0 (-103)
Houston Astros Team Preview
The Houston Astros have shown mixed results in their recent games. They lost to the New York Yankees on April 24th, 12-4, despite hitting two home runs. Lance McCullers Jr. struggled as the starting pitcher, allowing five earned runs in five innings.
On April 22nd, the Astros secured a 2-0 victory against the Cleveland Guardians. Peter Lambert delivered a strong performance on the mound, pitching six innings without giving up a run. Yordan Alvarez was the standout hitter, driving in both of the team’s runs with a home run.
The Astros have been effective at the plate this season, ranking fourth in batting average at .261. Their slugging percentage is third in the league, showing their strength in hitting for power. However, their pitching staff ranks last with a 5.97 ERA, highlighting an area for improvement.
BTB Betting Pick
The Yankees are favored with a moneyline of -152 against the Astros at +128. The Yankees have a strong pitching staff with a 3.11 ERA, ranked first in the league. Given their pitching advantage, the Yankees are the pick to win the game with a projected score of Yankees 5, Astros 4.
The total for the game is set at 9.0, with the over at -117 and the under at -103. The Astros have a high team ERA of 5.97, which suggests a higher-scoring game. Considering both teams’ offensive capabilities, the recommendation is to take the over, with a projected total of 9 runs.