New York Giants vs Detroit Lions Betting Pick & Prediction for 11/23

The New York Giants will head to Ford Field to take on the Detroit Lions in a Week 12 game of the 2025 NFL season. The game is set for Sunday, November 23, at 1:00 PM and will be broadcast on FOX. Despite the very cold day outside, the game will be played inside the dome, making weather conditions a non-factor.
The Giants, led by interim head coach Mike Kafka, have struggled this season with a 2-9 record and are winless on the road. Meanwhile, the Lions, under head coach Dan Campbell, have had a solid season with a 6-4 record. The Lions have performed well at home with a 3-1 record, giving them an advantage in this game.
New York Giants Team Preview
The New York Giants have struggled in recent games. They lost 27-20 to the Green Bay Packers at home. Jameis Winston threw for 201 yards but had one interception. Devin Singletary led the rushing attack with 44 yards and two touchdowns.
In their game against the Chicago Bears, the Giants were close but fell 24-20. Jaxson Dart passed for 242 yards without any touchdowns or interceptions. Darius Slayton was a standout with 89 receiving yards on four catches.
The Giants have a long list of injuries affecting their roster. Key players like Cam Skattebo and Malik Nabers are out for the season. Jaxson Dart is questionable with a concussion for the upcoming game. This could impact their performance on the field.
Giants vs Lions Game Day Info
- Sport: NFL
- Teams: New York Giants vs. Detroit Lions
- Venue: Ford Field in Detroit, MI
- Date: Sunday, November 23, 2025
- Betting Odds: Giants Moneyline +429, Lions Moneyline -580, Giants Spread +10.5 (-110), Lions Spread -10.5 (-109), Total Over 50.0 (-109), Total Under 50.0 (-110)
Detroit Lions Team Preview
The Detroit Lions have shown mixed results in their recent games. In Week 11, they lost to the Philadelphia Eagles 16-9. They had more passing yards than the Eagles but struggled on the ground, gaining only 74 rushing yards.
In Week 10, the Lions had a strong performance against the Washington Commanders, winning 44-22. They excelled in both passing and rushing, with 320 passing yards and 226 rushing yards. This victory was a team effort, with contributions from key players like Jared Goff and Jahmyr Gibbs.
Injury concerns are present for the Lions, with several key players on the injured reserve list. Sam LaPorta and Zach Cunningham are among those out for multiple games. The team will need to rely on their depth to maintain performance levels in upcoming games.
BTB Betting Pick
The Lions are favored by 10.5 points against the Giants. The Lions have the best offense in the league, scoring 564 points this season. The Giants rank 29th in scoring with 273 points. Given these numbers, the Lions are likely to cover the -10.5 spread. The projected score is Lions 35, Giants 21.
The total for the game is set at 50.0 points. The Lions have a strong offense, while the Giants have struggled to score. The Lions’ defense ranks 7th in opponent scoring, which could limit the Giants’ output. With these factors, the total score is expected to be under 50.0 points.