New York Giants vs Denver Broncos Betting Pick & Prediction for 10/19

The New York Giants will travel to Denver to take on the Broncos in Week 7 of the 2025 NFL season. The game will be held at Empower Field at Mile High, with a scheduled kickoff at 4:05 PM. Fans can catch the action on CBS, and the weather is expected to be clear and cool.
The Giants, led by Head Coach Brian Daboll, have had a challenging start with a 2-4 record. They have struggled on the road, going 0-3. The Broncos, with Sean Payton as head coach, hold a 4-2 record. They have been strong at home, remaining undefeated at 2-0. Denver is favored with a moneyline of -352, while the Giants sit at +281.
New York Giants Team Preview
The New York Giants recently won against the Philadelphia Eagles with a score of 34-17. Cam Skattebo led the team with 98 rushing yards and 3 rushing touchdowns. Jaxson Dart contributed with 195 passing yards and 1 touchdown.
In a prior game, the Giants lost to the New Orleans Saints, 26-14. Jaxson Dart had 202 passing yards and 2 touchdowns but also threw 2 interceptions. The Giants had more first downs than the Saints but struggled with turnovers.
The Giants have been dealing with several injuries. Key players like Graham Gano and Malik Nabers are out for extended periods. Darius Slayton is questionable with a hamstring injury for the upcoming game.
Giants vs Broncos Game Day Info
- Sport: NFL
- Teams: New York Giants vs. Denver Broncos
- Venue: Empower Field at Mile High in Denver, CO USA — Outdoor Field
- Date: Sunday, October 19, 2025 at 4:05 PM
- Betting Odds: Giants Moneyline +281, Broncos Moneyline -352, Giants Spread +7.0 (-113), Broncos Spread -7.0 (-108), Total Over 40.5 (-105), Total Under 40.5 (-115)
Denver Broncos Team Preview
The Denver Broncos have had a strong start to the season with several wins. In their recent game against the New York Jets, the Broncos won 13-11. Quarterback Bo Nix led the team with 174 passing yards and one touchdown.
Bo Nix has been a key player for the Broncos this season. He has passed for 1,277 yards and nine touchdowns across six games. J.K. Dobbins has also been effective, rushing for 442 yards and scoring four touchdowns.
The Broncos have faced some injuries that could impact their performance. Players like Michael Burton and Dre Greenlaw are on the injured reserve list. Despite these setbacks, the Broncos have shown strong team play in their games.
BTB Betting Pick
The Broncos are favored by 7 points in this game against the Giants. The Broncos have a strong offense, ranked 10th in scoring, while the Giants rank 29th. With the Broncos also having a top defense, ranked 3rd in opponent scoring, the pick is for the Broncos to cover the -7 spread. The projected score is Broncos 27, Giants 17.
The total for this game is set at 40.5 points. The Giants have struggled offensively, ranking 29th in scoring, while the Broncos have one of the top defenses. Given the Broncos’ solid defense and the Giants’ offensive struggles, the pick is for the game to go under 40.5 points. The projected total is 44 points.