Minnesota Twins vs Boston Red Sox Betting Pick & Prediction for 5/22

MLB game preview

The Minnesota Twins visit the Boston Red Sox in an MLB regular season game. This game takes place at Fenway Park in Boston, MA. Both teams are looking to improve their standings in their respective divisions.

The Twins have a record of 23-27 and are third in the AL Central. They recently won their last game and have a 6-4 record in their last ten games. The Red Sox, with a 22-27 record, are fourth in the AL East. They are on a three-game winning streak and have a 5-5 record in their last ten games.

Minnesota Twins Team Preview

The Minnesota Twins are coming off a win against the Houston Astros. In their last game, they won 4-1 with Joe Ryan pitching six strong innings. Ryan Kreidler and Victor Caratini each hit a home run to help secure the victory.

Throughout the season, the Twins have a batting average of .236, which places them 14th in the league. They have hit 55 home runs and have an on-base percentage of .322, ranking 9th. The team has also been effective at drawing walks with 185 so far this season.

On the mound, Connor Prielipp is the probable starter for the Twins in the next game. He holds a 2.88 ERA and a WHIP of 0.96 this season. Prielipp will aim to keep his strong performance going against the Boston Red Sox.

Twins vs Red Sox Game Day Info

  • Sport: MLB
  • Teams: Minnesota Twins vs. Boston Red Sox
  • Venue: Fenway Park in Boston, MA
  • Date: Friday, May 22, 2026
  • Betting Odds: Twins Moneyline +131, Red Sox Moneyline -155

Boston Red Sox Team Preview

The Boston Red Sox have been performing well in their recent games. They have secured wins against the Kansas City Royals in their last three games. In their most recent game on May 20th, the Red Sox won 4-3 with strong performances from Jarren Duran and Willson Contreras.

The Red Sox have shown strength in hitting, with a batting average of .240 this season. They rank 12th in batting average and have hit 84 doubles, ranking 6th in the league. Willson Contreras leads the team in home runs with 10 and has been a key player in their lineup.

On the pitching side, Payton Tolle stands out with a 2.05 ERA and 30 strikeouts this season. The Red Sox’s pitching staff ranks 9th in earned run average at 3.67. They have also been effective at limiting opponents’ batting averages to .233, ranking 10th in the league.

BTB Betting Pick

The Red Sox are favored to win against the Twins with a moneyline of -155. The Twins have a moneyline of +131. The Red Sox have a better pitching record with a 3.67 ERA compared to the Twins’ 4.20 ERA. This gives them an edge in this game. My pick is the Red Sox to win.

The total for the game is set at 7.5. The Twins have a higher home run ranking, which could lead to more scoring. The Red Sox have a solid batting average against, which may limit the Twins’ scoring chances. With the current line and team stats, I recommend taking the under 7.5.