Minnesota Golden Gophers vs Ohio State Buckeyes Betting Pick & Prediction for 10/4

In Week 6 of the 2025 regular season, the Minnesota Golden Gophers will travel to face the Ohio State Buckeyes. The game will take place at Ohio Stadium in Columbus, Ohio, on Saturday, October 4th, at 7:30 PM. Fans can catch the action on NBC as these Big Ten teams meet under the lights.
Minnesota comes into the game with a 3-1 record, having won all their home games but struggling on the road with a 0-1 record. Ohio State is ranked number one in both the AP and Coaches Polls, boasting a perfect 4-0 record. The Buckeyes have been dominant at home with a 3-0 record and will look to continue their strong performance in this conference showdown.
Minnesota Team Preview
The Minnesota Golden Gophers have shown a mix of results this season. They won against Rutgers with a score of 31-28. However, they faced a loss to California, ending the game 27-14.
Quarterback Drake Lindsey is a key player for the Gophers. He has thrown for 958 yards and seven touchdowns. Lindsey has only been intercepted twice in four games.
Injuries might affect the team in upcoming games. Players like Mo Omonode and A.J. Turner are out for the season. Several others, including Darius Taylor, are questionable due to injuries.
Minnesota vs Ohio State Game Day Info
- Sport: NCAA Football
- Teams: Minnesota Golden Gophers vs. Ohio State Buckeyes
- Venue: Ohio Stadium in Columbus, OH
- Date: Saturday, October 4, 2025
- Betting Odds: Minnesota +1280, Ohio State -3146
Ohio State Team Preview
The Ohio State Buckeyes have had a strong start to the 2025 season. They won their recent game against the Washington Huskies with a score of 24-6. The Buckeyes had 23 first downs and gained 208 passing yards in that game.
Earlier this season, the Buckeyes had a big win against the Ohio Bobcats with a 37-9 score. In that game, they racked up 347 passing yards and 226 rushing yards. The Buckeyes also managed to secure 28 first downs.
Ohio State’s offense has been performing well, with 145 points scored this season. Their defense has also been strong, allowing only 22 points against them. The team’s next game will be important as they continue their season.
BTB Betting Pick
For the spread, Minnesota at +23.5 (-109) is the pick to cover. Ohio State has a strong defense, allowing only 22 points this season, but Minnesota’s defense is also solid, ranking high in sacks and interceptions. The projected score is Ohio State 28, Minnesota 14, which keeps Minnesota within the spread.
The over/under line is set at 43.5. The combined projected score of 42 points suggests taking the under at 43.5 (-113) is the better choice. Both teams have strong defenses, with Ohio State ranking 4th in points against and Minnesota ranking 36th, making a high-scoring game unlikely.