Michigan Wolverines vs USC Trojans Betting Pick & Prediction for 10/11

College Football Preview

In Week 7 of the 2025 regular season, the Michigan Wolverines travel to face the USC Trojans. The game takes place at the Los Angeles Memorial Coliseum on Saturday, October 11, 2025. Kickoff is scheduled for 7:30 PM and will be broadcast on NBC.

Both teams enter this game with a 4-1 record. Michigan is ranked 15th in both the AP and Coaches polls. The Wolverines have a 1-1 record on the road this season. Meanwhile, USC has been strong at home with a 3-0 record. The Trojans aim to maintain their winning form in front of their fans.

Michigan Team Preview

The Michigan Wolverines have been doing well this season. They won against Wisconsin with a score of 24-10. In this game, they managed 270 passing yards and 175 rushing yards. They also had two fumbles but no interceptions.

In their game against Nebraska, Michigan won 30-27. They had 105 passing yards and a strong 290 rushing yards. Despite having fewer first downs than Nebraska, their solid rushing game helped them win.

Against Central Michigan, Michigan had a dominant performance, winning 63-3. They gained 235 passing yards and 390 rushing yards. This game highlighted their ability to control the field with both passing and rushing strategies.

Michigan vs USC Game Day Info

  • Sport: NCAA Football
  • Teams: Michigan Wolverines vs. USC Trojans
  • Venue: Los Angeles Memorial Coliseum, Los Angeles, CA
  • Date: Saturday, October 11, 2025
  • Betting Odds: Michigan Moneyline +116, USC Moneyline -139, Michigan Spread +2.5 (-109), USC Spread -2.5 (-111), Total Over 57.5 (-111), Total Under 57.5 (-110)

USC Team Preview

The USC Trojans have had a strong start to their season. They scored a big win against Michigan State Spartans, 45-31, at home. In their home opener, they dominated Missouri State Bears, winning 73-13. The Trojans’ offense is ranked 5th in points for the 2025 season.

Quarterback Jayden Maiava has been a key player for the Trojans. He has passed for 1,587 yards and has thrown 11 touchdowns in five games. Maiava ranks 1st in the league for passing yards on his team. Waymond Jordan, a running back, leads the team with 537 rushing yards.

The Trojans have faced some challenges with injuries. Several players, including Bryan Jackson and Zacharyus Williams, are listed as questionable. Chasen Johnson will miss the rest of the season due to a knee injury. Despite these setbacks, the Trojans continue to perform well on both offense and defense.

BTB Betting Pick

For the spread pick, take Michigan +2.5. Michigan’s defense ranks well in sacks and interceptions, which can help slow down USC’s offense. With the spread at +2.5, Michigan has a good chance to cover, even if they do not win outright. The projected score is USC 31, Michigan 30.

For the over/under pick, go with the over at 57.5. USC has a high-scoring offense, ranking 5th in points for the season. Michigan also has a strong running game, which can lead to points. The projected total is 61, slightly above the current line of 57.5.