Los Angeles Chargers vs Arizona Cardinals Betting Pick & Prediction 10/21/24
This article was published on Oct 15, 2024. Today’s picks NFL picks

ESPN will broadcast the week seven non-conference matchup between the Chargers and Cardinals from State Farm Stadium in Glendale, AZ. The Cardinals are the home team and the game is set for 9:00 ET. The Chargers are favored on the road with a point spread of -2.5 and have a money line of -147. The Cardinals’ money line odds are +123, and the over/under line is 43.5 points.
LOS ANGELES CHARGERS VS ARIZONA CARDINALS BETTING PICK
The Pick: Los Angeles Chargers -2.5
This game will be played at State Farm Stadium at 9:00 ET on Monday, October 21st.
WHY BET THE LOS ANGELES CHARGERS:
- We have the Chargers winning this one by a score of 27 to 23
- Not only do we have the Chargers winning straight-up, we have them covering the spread at -2.5
- Look for this game to go over the line of 43.5 points
Will The Chargers Pick Up A Win On The Road?
After two straight losses, the Chargers got back on track with a 23-16 win over the Broncos in week 6, bringing their record to 3-2. This puts them 2nd in the AFC West and 6th in the conference. According to our projections, L.A. has a 58.2% chance of making the playoffs and a 4.6% chance of winning the division. They rank 20th in our NFL power rankings heading into week 7.
So far, the Chargers have a +5 scoring margin and are 3-1-1 against the spread. They are 3-0 ATS as favorites, including a win over Denver, where they covered the 3-point spread. Their O/U record is 1-4, with their games averaging 31.4 points compared to an average line of 38.7.
Heading into week 7, the Chargers rank 23rd in our offensive power rankings, averaging 18.2 points per game. They sit 28th in the NFL in total offense with 281 yards per game and are 29th in passing yards, with 153.2 per game on 25.4 attempts. On the ground, they rank 10th in rushing yards, averaging 127.8 per game on 30.6 attempts. The Chargers have been strong on 3rd down, converting 42.5% of their attempts, and they rank 3rd in the NFL in red zone conversion percentage.
In week 6, Justin Herbert threw for 237 yards and a touchdown, completing 21 of 34 passes. J.K. Dobbins rushed for 96 yards on 25 carries, while Simi Fehoko led the team in receiving with 44 yards. The Chargers scored 20 points in the first half against Denver but were held scoreless in the 4th quarter.
Despite allowing 110 rushing yards to the Broncos on just 18 attempts, the Chargers’ defense played well in their 23-16 win. They held Denver to 27.3% on third down and limited them to 16 completions on 35 attempts for 206 yards. The Chargers also came up with one interception and recorded two sacks.
Two of the Broncos’ touchdowns came through the air. Overall, the Chargers defended the pass well, allowing a completion percentage of just 57.6%.
Will The Cardinals Win At Home Over The Chargers?
Heading into week 7 with a 2-4 record, the Cardinals have a 24.7% chance of making the playoffs and a 20.5% chance of winning the NFC West. Despite their losing record, Arizona is 2-0 in division games, including a 31-point win over the Rams in week 2. However, they couldn’t build on their week 5 win over the 49ers, falling to the Packers 34-13 in week 6.
In our power rankings, the Cardinals sit 19th going into week 7. Their average scoring margin is -5, and they are 3-3 against the spread. Their O/U record is 3-2-1, with their games averaging 49.3 points per game.
Heading into week 7, the Cardinals sit 16th in our offensive power rankings, averaging 22.2 points per game, which ranks 15th in the NFL. They also rank 15th in yards per game, with 332.2. Arizona has leaned on their run game, averaging 145.2 rushing yards per game, which ranks 7th, on 27.3 attempts per game. On the passing side, they rank 24th in both passing attempts (28.3) and passing yards per game (187). The Cardinals are 13th in the NFL in 3rd-down conversions, with a 40.6% success rate, and they rank 13th in red zone conversion percentage.
Kyler Murray threw for 214 yards and a touchdown in week 6, completing 22 of 32 passes without an interception. Arizona struggled to run the ball, with Trey Benson leading the team with just 26 yards on 5 carries. Tight end Trey McBride led the team in receiving, with 8 catches for 96 yards. The Cardinals failed to score in the 1st and 4th quarters in their 34-13 loss to the Packers.
In their 34-13 loss to the Packers, the Cardinals’ defense struggled to defend the pass, giving up four touchdowns through the air. They allowed 258 passing yards on 22 completions, and Green Bay averaged 8.1 yards per pass attempt. Arizona’s defense also struggled to get off the field, as the Packers converted 58.3% of their third down attempts.
On the ground, the Cardinals gave up 179 rushing yards on 38 attempts, with Green Bay finishing with 437 total yards. Arizona’s defense didn’t record any sacks in the game, but they did come up with one interception.
