Kentucky Wildcats vs Vanderbilt Commodores Betting Pick & Prediction for 11/22

College Football Preview

The Kentucky Wildcats are set to take on the Vanderbilt Commodores in Week 13 of the 2025 regular season. The game will be held at FirstBank Stadium in Nashville, Tennessee. Fans can catch the action on ESPN at 3:30 PM on Saturday, November 22.

Kentucky enters the game with a 5-5 record, having struggled in conference play with a 2-5 record. Vanderbilt holds an 8-2 record and remains unbeaten at home this season. The Commodores are ranked #12 in the AP Poll and #13 in the Coaches Poll.

Kentucky Team Preview

The Kentucky Wildcats have been performing well in their recent games. They secured a win against Tennessee Tech with a score of 42-10. In that game, they had 261 passing yards and 207 rushing yards, showing a balanced offense.

Another notable game was against the Florida Gators, where they won 38-7. Kentucky’s rushing game was strong, gaining 235 yards. Their defense also did well, with three interceptions against Florida.

However, Kentucky faced a tough challenge against Auburn but still managed to win 10-3. Their defense held Auburn to only three points, despite having fewer first downs. Kentucky’s ability to win in close games shows their determination on the field.

Kentucky vs Vanderbilt Game Day Info

  • Sport: NCAA Football
  • Teams: Kentucky Wildcats vs. Vanderbilt Commodores
  • Venue: FirstBank Stadium in Nashville, TN
  • Date: Saturday, November 22, 2025
  • Betting Odds: Kentucky +290, Vanderbilt -371

Vanderbilt Team Preview

The Vanderbilt Commodores have had a mixed season so far. They recently pulled off a 45-38 win against Auburn at home. Their performance at FirstBank Stadium has been a strong point this season.

Offensively, the Commodores rank 12th in points for with 383 points. Diego Pavia, their top quarterback, has thrown for 2,440 yards in ten games. Their running backs, Sedrick Alexander and Makhilyn Young, have been consistent, with Alexander leading with 441 rushing yards.

On the defensive side, Vanderbilt ranks 82nd in points against, allowing 222 points this season. They are strong in interceptions, ranked 5th with 4 interceptions. However, they have some players listed as questionable, which might affect their next game. Drew Dickey, Chase Gillespie, and others are dealing with undisclosed injuries.

BTB Betting Pick

The spread for this game is Kentucky +9.5. Vanderbilt has a strong offense, ranked 12th in points scored, while Kentucky’s defense is ranked 87th in points against. With Vanderbilt’s offensive strength, they are projected to win 31-20. The recommendation is to take Vanderbilt to cover the spread.

The total for the game is set at 53.5. Vanderbilt’s games have seen high scoring with their strong offense. Kentucky’s defense has been allowing points, ranked 87th in points against. The projected total is 51, so the recommendation is to take the under.