Jacksonville Jaguars vs Buffalo Bills Betting Pick & Prediction 9/23/24
This article was published on Sep 17, 2024. Today’s picks NFL picks

The Jaguars and Bills will face off on Monday, September 23rd at 7:30 ET, with ESPN providing the TV coverage. The Bills are the heavy favorite with a point spread of -5.5 and a money line of -257. This week three AFC matchup is being played at Highmark Stadium in Orchard Park, NY, and the over/under line is set at 45.5 points.
JACKSONVILLE JAGUARS VS BUFFALO BILLS BETTING PICK
The Pick: Jacksonville Jaguars +5.5
This game will be played at Highmark Stadium at 7:30 ET on Monday, September 23rd.
WHY BET THE JACKSONVILLE JAGUARS:
- We have the Bills winning this one by a score of 28 to 25
- Even though we like the Bills to win, our ATS pick is to take the Jaguars at +5.5
- Look for this game to go over the line of 45.5 points
Will The Jaguars Pull Off An Upset As Road Underdogs
The Jaguars’ 18-13 loss to the Browns dropped their record to 0-2 for the season. Jacksonville fell behind early, as Deshaun Watson’s 1-yard touchdown gave Cleveland a 7-0 lead in the 1st quarter. The Jaguars added a field goal in the 2nd quarter but still trailed 13-3 at halftime. Jacksonville fought back in the 3rd quarter, with Trevor Lawrence finding Brian Thomas Jr. for a touchdown to make it 16-10. They added a field goal in the 4th to pull within three, but a late Browns touchdown sealed the win for Cleveland.
Jacksonville was favored by -3, and the game’s 31 total points fell short of the over/under line of 41.5 points. The Jaguars failed to cover the spread with their 5-point loss.
The Jaguars’ offense struggled in their 18-13 loss to the Browns, managing just 13 points. They had 18 first downs and 127 yards on the ground, averaging 6.0 yards per attempt, but their passing game was inefficient. Quarterback Trevor Lawrence completed only 46% of his passes for 220 yards, with no touchdowns. Lawrence was sacked four times and finished with a passer rating of 71.
Travis Etienne Jr. led the team with 52 rushing yards on 13 attempts, including a long run of 20 yards and one touchdown. Brian Thomas Jr. was the top receiver with 94 yards, 66 of which came on a single catch. The Jaguars collectively struggled on third down, converting only 33.3% of their attempts.
In their 18-13 loss to the Browns, the Jaguars’ defense didn’t allow a touchdown through the air, giving up just 172 passing yards. They struggled to defend the run, allowing 125 yards on 29 attempts. Overall, the Jaguars gave up 297 total yards to Cleveland. Jacksonville’s defense was tough on third downs, allowing just a 14.3% conversion rate, but they still couldn’t come out on top in this one. The Jaguars also had two sacks in the game.
Are The Bills Going To Defend Home Field Advantage?
The Bills came out on top in their most recent game, beating the Dolphins 31-10 and moving to 2-0 for the season. Despite being +2.5 point underdogs on the road, Buffalo won by 21 points, easily covering the spread. The game finished with a combined 41 points, falling short of the over/under line of 49 points. Buffalo’s strong performance allowed them to take a 24-10 lead at halftime and cruise to the win from there.
Josh Allen’s 17-yard touchdown pass to James Cook and a 34-yard touchdown pass to Ty Johnson were key moments in the 2nd quarter after the game was tied 7-7 early on. The Bills’ defense also played well, forcing Tua Tagovailoa into a critical turnover in the 3rd quarter just as the Dolphins were looking to make a comeback.
Josh Allen completed 13 of 19 passes for 139 yards and one touchdown in Buffalo’s 31-10 win over the Dolphins. The Bills’ offense managed just 13 first downs and 108 yards on the ground, but they were efficient in the passing game, with Allen posting a passer rating of 107 and not being sacked. Khalil Shakir led the team with 54 receiving yards.
Running back James Cook had a good game, rushing for 78 yards on 11 carries, including a 49-yard run and two rushing touchdowns. He also added a receiving touchdown. The Bills struggled on third down, converting only 33.3% of their chances.
In their 31-10 win over the Dolphins, the Buffalo Bills’ defense picked off three passes and held Miami to just 5.4 yards per attempt. Despite giving up 139 rushing yards on 34 attempts, Buffalo’s defense was able to limit the Dolphins to just 10 points. They also had two sacks and held Miami to a 46.7% third-down conversion rate.
Buffalo’s defense also forced 25 completions for 212 passing yards. They allowed one passing touchdown and held Miami to a 64.1% completion rate. The Bills’ defense also had five more quarterback hits than Miami and six more tackles for loss.
