Iowa State Cyclones vs Colorado Buffaloes Betting Pick & Prediction for 10/11

College Football Preview

The Iowa State Cyclones travel to Boulder to take on the Colorado Buffaloes in Week 7 of the 2025 regular season. The game is set for Saturday, October 11, 2025, at 3:30 PM. Fans can catch the action live on ESPN from Folsom Field.

Iowa State enters the game ranked #22 in the AP Poll with a 5-1 record this season. They have performed well in their conference games, holding a 2-1 record. Colorado, on the other hand, is struggling with a 2-4 record and has not yet won a conference game this season. Both teams are part of the Big 12 Conference.

Iowa State Team Preview

The Iowa State Cyclones have a record of 4-1 in their last five games. They scored a big win against Arizona Wildcats, 39-14, at home. Their only loss came against the Cincinnati Bearcats, where they fell 38-30 on the road. Despite the loss, the Cyclones showed strength in their passing game with 314 yards.

Rocco Becht leads the team at quarterback with 1,417 passing yards and nine touchdowns. His performance ranks him 20th in the league for passing yards. Carson Hansen is the top rusher with 348 yards, contributing to the team’s balanced offensive attack.

The Cyclones face some injury concerns with several players listed as questionable, including key receivers and defenders. Their defense ranks 59th in points against, but they have been effective in forcing turnovers with six interceptions. This defensive effort will be crucial in their upcoming games.

Iowa State vs Colorado Game Day Info

  • Sport: NCAA Football
  • Teams: Iowa State Cyclones vs. Colorado Buffaloes
  • Venue: Folsom Field in Boulder, CO
  • Date: Saturday, October 11, 2025
  • Betting Odds: Iowa State -160, Colorado +135, Spread: Iowa State -3.5 (-105), Colorado +3.5 (-115), Total: 52.5 (-110) Over/Under

Colorado Team Preview

The Colorado Buffaloes have shown a mix of performances this season. In their recent game against TCU, they lost 35-21. They managed 217 passing yards and 126 rushing yards but had three interceptions, which hurt their chances.

Earlier, they faced BYU at home and lost narrowly, 24-21. The team gained 119 passing yards and 172 rushing yards. Despite these efforts, they couldn’t secure the win, with one interception on their record.

Their last victory came against Wyoming, with a score of 37-20. In that game, they excelled with 304 passing yards and 193 rushing yards. The team showed discipline with no interceptions, leading to a solid win.

BTB Betting Pick

The Iowa State Cyclones are favored by 3.5 points against the Colorado Buffaloes. Iowa State’s offense ranks 25th in points for, while Colorado’s defense ranks 92nd in points against. Given these stats, Iowa State should cover the -3.5 spread. The projected score is Iowa State 28, Colorado 24.

The total for the game is set at 52.5 points. Iowa State has scored 188 points this season, and Colorado has scored 150. Both teams have solid offenses, but Iowa State’s defense ranks 59th in points against. This suggests the total will go over 52.5. The projected total score is 52, which is close to the line.