Indiana Pacers vs Cleveland Cavaliers Betting Pick & Prediction for 11/21

The Indiana Pacers will take on the Cleveland Cavaliers at Rocket Arena on Friday, November 21, 2025, at 7:00 PM. The Pacers, led by Head Coach Rick Carlisle, have struggled early this season with a 2-13 record. They are looking to build on their recent win against the Charlotte Hornets. The Pacers are currently ranked 14th in the Eastern Conference.
The Cleveland Cavaliers, coached by Kenny Atkinson, hold a 10-6 record. They are ranked 4th in the Eastern Conference. The team hopes to bounce back from a recent loss to the Houston Rockets. Donovan Mitchell and Evan Mobley will be key players for the Cavaliers as they return to their home court. Fans can catch the game live on Amaz.
Pacers vs Cavaliers Game Day Info
- Sport: NBA
- Teams: Indiana Pacers vs. Cleveland Cavaliers
- Venue: Rocket Arena
- Date: Friday, November 21, 2025
- Betting Odds: Cavaliers -13.5 (-111), Pacers +13.5 (-110), Cavaliers MoneyLine -875, Pacers MoneyLine +582, Over/Under 237.5
Indiana Pacers Team Preview
The Indiana Pacers are preparing for their next game against the Cleveland Cavaliers. The Pacers recently secured a win over the Charlotte Hornets with a score of 127-118. Bennedict Mathurin played a key role, contributing 24 points and 12 rebounds in that victory.
In the current season, the Pacers have faced some challenges. They rank 28th in points per game, scoring 110.1 on average. Their field goal percentage is 41.1, placing them at the bottom of the league in that category.
Pascal Siakam stands out as a top performer for the Pacers this season. He averages 24.7 points and 6.9 rebounds per game. The team is dealing with multiple injuries, including Tyrese Haliburton, who will miss the entire season.
Cleveland Cavaliers Team Preview
The Cleveland Cavaliers recently faced a tough loss against the Houston Rockets. They scored 104 points with a field goal percentage of 44.4%. De’Andre Hunter led the team with 25 points, while Donovan Mitchell added 21 points.
In a game against the Milwaukee Bucks, the Cavaliers secured a win by scoring 118 points. Donovan Mitchell shined with 37 points and 7 assists. Sam Merrill also contributed with 20 points and an impressive 70% shooting accuracy.
Throughout the season, the Cavaliers have averaged 119.9 points per game, placing them 9th in the league. Donovan Mitchell has been a standout player, averaging 30.2 points per game. However, injuries have been a concern, with key players like Jarrett Allen and Darius Garland listed as questionable for upcoming games.
BTB Betting Pick
The Cavaliers are favored by 13.5 points against the Pacers. The Pacers have struggled offensively, ranking 28th in points per game. Meanwhile, the Cavaliers score 119.9 points per game, ranking 9th. With the Cavaliers’ strong scoring and the Pacers’ weak defense, the Cavaliers are likely to cover the spread. Projected score: Cavaliers 125, Pacers 108.
The total for the game is set at 237.5 points. The Pacers allow 123.1 points per game, while the Cavaliers allow 116.1 points. Both teams have high possession rates, suggesting a fast-paced game. Considering these factors, the game is likely to go over the total. Projected total: 233 points.