Indiana Hoosiers vs Penn State Nittany Lions Betting Pick & Prediction for 11/8

Week 11 of the 2025 NCAA football season features a game between the Indiana Hoosiers and the Penn State Nittany Lions. The game will take place at Beaver Stadium in University Park, PA, on Saturday, November 8, 2025, at 12:00 PM. Fans can catch the action on FOX.
Indiana enters the game with an impressive 9-0 record and holds the number two spot in both the AP and Coaches Polls. The Hoosiers are undefeated in conference play with a 6-0 record. On the other side, Penn State has faced challenges this season, holding a 3-5 record and struggling in conference games. They aim to defend their home turf, where they have a 3-2 record this season.
Indiana Team Preview
Indiana Hoosiers are on a strong winning streak, taking victories in their last five games. Their latest game was a dominant 55-10 win against Maryland Terrapins. The Hoosiers excelled with 369 rushing yards compared to Maryland’s 37, showing their ground game strength.
The Hoosiers’ offense is leading the league with 418 points scored this season. Fernando Mendoza, their top quarterback, has been effective with 2,124 passing yards and 25 touchdowns. On the ground, Kaelon Black leads the rushing attack with 619 yards over nine games.
Indiana’s defense ranks high in several categories, with 29 sacks this season. They are also ranked seventh in fumbles recovered, showing their ability to disrupt opposing offenses. However, they face some injury concerns, including key players like Bryson Bonds and Elijah Sarratt who are currently out or questionable.
Indiana vs Penn State Game Day Info
- Sport: NCAA Football
- Teams: Indiana Hoosiers vs. Penn State Nittany Lions
- Venue: Beaver Stadium in University Park, PA
- Date: Saturday, November 8, 2025
- Betting Odds: Indiana Moneyline -704, Penn State Moneyline +496, Indiana Spread -14.5 (-111), Penn State Spread +14.5 (-109), Total Over 49.5 (-106), Total Under 49.5 (-114)
Penn State Team Preview
Penn State has faced some tough competition recently. They lost to Ohio State 38-14, managing 145 passing yards and 55 rushing yards. Their defense allowed Ohio State to gain 316 passing yards and 167 rushing yards.
In a close game against Iowa, Penn State lost 25-24. They recorded 93 passing yards and 173 rushing yards, but had two interceptions. Despite the loss, they had more first downs than Iowa, with a total of 19.
Penn State’s matchup against Northwestern ended with a 22-21 loss. They achieved 137 passing yards and 137 rushing yards. The team also recorded one interception and a fumble in this game.
BTB Betting Pick
For the spread pick, Indiana is favored by 14.5 points. With Indiana’s strong offensive stats, ranking first in points for and first downs, they have the potential to cover this spread. The projected score is Indiana 35, Penn State 17, suggesting Indiana will cover the -14.5 spread.
For the total points, the line is set at 49.5. Indiana’s powerful offense, combined with Penn State’s defense allowing 174 points this season, points to a higher scoring game. The projected total is 52 points, so taking the over 49.5 is recommended.