Houston Cougars vs Colorado Buffaloes Prediction & Odds – November 13, 2026
Houston Cougars to win Moneyline -380
Bet Houston Cougars at BetOnlineOdds checked Nov 12, 8:01 AM ET. Prices vary by sportsbook, so compare before you bet.
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Houston arrives at Folsom Field with a 7-2 record, while Colorado is 3-6. The Cougars bring the stronger overall mark, but their 2-2 road record leaves room for a contest in Boulder.

Game details and odds
Friday, November 13, 2026 at 10:15 pm EST · Folsom Field
| Team | Spread (American price) | Moneyline |
|---|---|---|
| Houston Cougars | -9.5 (-112) | -380 |
| Colorado Buffaloes | +9.5 (-108) | +300 |
Total: 51.5 — over -102, under -118.
Draft Kings odds checked November 12, 2026 13:01 UTC. Odds subject to change.
Houston’s scoring balance faces a road test
Houston averages 35.4 points and 470.2 yards per game, with 207.7 yards coming on the ground. Conner Weigman has thrown 22 touchdowns against two interceptions, giving the Cougars a productive passing threat alongside their rushing attack. Their defense allows 21.3 points per game, another advantage in the season profile.
The Cougars rebounded from a 21-13 loss at Utah by beating Cincinnati 31-24 in their latest completed game. Their other recent road result was more convincing: a 35-16 win at Kansas State. Houston also beat Oklahoma State 35-32 and UCF 27-17 at home, showing it can win both tight games and less frantic ones. Still, the Utah result is a useful check on expectations. Houston did not generate enough points in that trip, so its scoring rhythm away from home remains an important part of this matchup.
Our pick: Houston Cougars to win.
Bet Houston Cougars at BetOnlineColorado’s home competitiveness meets a scoring challenge
Colorado averages 255.4 passing yards per game, and Joseph Williams has 58 catches for 853 yards and six touchdowns. That production offers a path to sustained offense, but the Buffaloes average 19.8 points while allowing 28.3. Turning passing yardage into points is the central challenge against Houston’s more prolific attack.
Colorado’s last home game ended in a 27-24 win over Kansas State, proof that it can finish a close contest at Folsom Field. The Buffaloes also pushed Utah in a 27-24 home loss. Those results offer more encouragement than their latest outing, a 20-10 defeat at Arizona State, where scoring was again limited. A 57-24 loss at Oklahoma State and a 29-7 home loss to Texas Tech show how quickly games can get away from Colorado when either side of the ball falters. Keeping Houston within reach will require a steadier performance.
Injury news
Houston Cougars: No player statuses returned in the latest check..
Colorado Buffaloes: No player statuses returned in the latest check..
Availability checked November 12, 2026 13:01 UTC. Reported statuses may change; final lineups are not confirmed here.
BTB Betting Pick
Winner pick: Houston Cougars.
Houston’s stronger scoring profile and its win at Kansas State make the Cougars the pick. Colorado’s close home games against Kansas State and Utah, however, suggest this need not be straightforward.
Original winner pick recorded November 12, 2026 06:03 UTC. Subsequent updates retain that selection.