Detroit Red Wings vs St. Louis Blues Betting Pick & Prediction for 10/28/2025

The Detroit Red Wings are set to take on the St. Louis Blues at the Enterprise Center. This game marks the start of the NHL Regular Season. The Red Wings come into the game with a record of 6-3-0, while the Blues hold a record of 3-5-1.
Detroit’s head coach, Todd McLellan, leads the team from the Eastern Atlantic Division. On the other side, Jim Montgomery guides the Blues in the Western Central Division. The game will air on ESPN+ at 8:15 PM on Tuesday, October 28, 2025.
Red Wings vs Blues Game Day Info
- Sport: NHL
- Teams: Detroit Red Wings vs. St. Louis Blues
- Venue: Enterprise Center
- Date: Tuesday, October 28, 2025
- Betting Odds: Detroit Red Wings MoneyLine +100, St. Louis Blues MoneyLine -120
Detroit Red Wings Team Preview
The Detroit Red Wings have had a mixed start to their season. They recently won against the St. Louis Blues, 6-4. However, they lost to the New York Islanders and Buffalo Sabres in back-to-back games.
Dylan Larkin is leading the Red Wings with 13 points in nine games. Emmitt Finnie has contributed eight points, showing his ability to assist. Alex DeBrincat, while not scoring many goals, has been helpful with seven assists.
In goal, Cam Talbot and John Gibson have shared responsibilities. Talbot has three wins and one loss with 105 saves. Gibson also has three wins but two losses, with a total of 107 saves.
St. Louis Blues Team Preview
The St. Louis Blues are looking to bounce back after a string of losses. They have faced tough opponents like the Pittsburgh Penguins and Detroit Red Wings recently. The team has been struggling, with their last win against the Dallas Stars.
In the current season, the Blues have scored 27 goals, ranking 11th overall. Their power play goals stand at 6, placing them 6th in the league. On defense, they have 229 hits, ranking them 7th, showing their physical play.
Among the top players, Jordan Kyrou has 7 points in 9 games. Jake Neighbours and Robert Thomas each have 7 and 6 points, respectively. In goal, Jordan Binnington has played 7 games with 2 wins, while Joel Hofer has 1 win in 4 games.
BTB Betting Pick
For the moneyline pick, the St. Louis Blues are favored with a line of -120. The Blues have shown strong performance, ranking 9th in goals against. The projected score is St. Louis 3, Detroit 2. With the Blues’ defensive edge, they are the pick to win straight up.
In the over/under market, the total is set at 6.0. The projected score is 3-2 in favor of St. Louis, totaling 5 goals. Both teams have solid goaltending stats, so the under 6.0 (-110) is the recommendation here.