Cincinnati Reds vs Seattle Mariners Betting Pick & Prediction for 7/22

MLB game preview

The Cincinnati Reds will take on the Seattle Mariners in an MLB regular season game. The game will be held at T-Mobile Park in Seattle. The Mariners have a record of 51-50 and are currently second in the AL West.

The Reds have a record of 45-54 and are fifth in the NL Central. Brady Singer will pitch for the Reds. Emerson Hancock will start for the Mariners. The game is scheduled for Wednesday, July 22, 2026, at 3:40 PM. Weather conditions are expected to be clear.

Cincinnati Reds Team Preview

The Cincinnati Reds have had a mixed run in their recent games. They secured a 9-6 victory against the Colorado Rockies on July 19th. However, they faced a tough loss of 8-0 to the Seattle Mariners on July 20th, with only three hits in the game.

Brady Singer is expected to start for the Reds in the upcoming game. This season, Singer has a 4-9 record with a 4.56 ERA. He will aim to improve on his performance and give the Reds a better chance at winning.

The Reds have shown strength in hitting home runs, ranking 8th in the league with 129 home runs. Sal Stewart leads the team with 20 home runs. The team also has a high number of walks, placing 8th in the league with 360 walks this season.

Reds vs Mariners Game Day Info

  • Sport: MLB
  • Teams: Cincinnati Reds vs. Seattle Mariners
  • Venue: T-Mobile Park in Seattle, WA
  • Date: Wednesday, July 22, 2026
  • Betting Odds: Reds Moneyline +130, Mariners Moneyline -156, Reds Runline +1.5 (-165), Mariners Runline -1.5 (+138), Total Over 8.0 (-112), Total Under 8.0 (-109)

Seattle Mariners Team Preview

The Seattle Mariners have been on a good run in their recent games. They have secured wins against the Cincinnati Reds and San Francisco Giants. Their most recent game ended in an 8-0 win over the Reds, with George Kirby pitching six scoreless innings.

The Mariners’ batting has been effective, with standout performances from players like Cal Raleigh and Victor Robles. In their game on July 20th, Robles had four hits, while Raleigh drove in five runs with a home run. Their overall team batting average stands at .230, ranking 21st in the league.

On the pitching side, the Mariners have one of the best ERAs in the league at 3.57, ranking 5th. Emerson Hancock will start the next game, bringing a 3.17 ERA and 94 strikeouts this season. Their pitchers have given up the fewest home runs, showing strength in their defense.

BTB Betting Pick

The Mariners are favored with a moneyline of -156 against the Reds, who are at +130. The Mariners have a better pitching staff, ranking 5th in ERA, while the Reds are 23rd. Based on these stats, the Mariners are the pick to win the game with a projected score of 5-3.

The total for the game is set at 8.0 runs. The Reds’ pitching has allowed a high number of runs with a 4.61 ERA. With both teams having a decent number of home runs, the over is the pick here. Expect the total to exceed 8.0 runs in this game.