Arizona Cardinals vs Seattle Seahawks Betting Pick & Prediction for 11/9

The Arizona Cardinals are set to play the Seattle Seahawks in Week 10 of the 2025 NFL season. This game will take place at Lumen Field in Seattle. The weather forecast predicts a cool day with overcast clouds, creating an interesting setting for this division game. Fans can catch the action on CBS at 4:05 PM on Sunday, November 9.
The Cardinals, led by head coach Jonathan Gannon, have a current record of 3-5. They are seeking to improve their standing in the NFC West. On the other side, the Seahawks, with head coach Mike Macdonald, hold a 6-2 record. They aim to maintain their strong performance this season. With both teams in the same division, this game holds importance for their playoff hopes. The consensus odds favor the Seahawks, with a moneyline of -312, while the Cardinals sit at +251.
Arizona Cardinals Team Preview
The Arizona Cardinals are coming off a win against the Dallas Cowboys, where they scored 27-17. Jacoby Brissett led the offense with 261 passing yards and two touchdowns. Marvin Harrison Jr. contributed with 96 receiving yards and a touchdown.
In their previous games, the Cardinals faced a few close losses. They lost to the Green Bay Packers 27-23 and to the Indianapolis Colts 31-27. Despite these losses, Jacoby Brissett performed well, throwing for over 270 yards in both games.
The Cardinals are dealing with injuries that impact their lineup. Key players like James Conner and Trey Benson are out for the season. Quarterback Kyler Murray is questionable with a foot injury for the upcoming game.
Cardinals vs Seahawks Game Day Info
- Sport: NFL
- Teams: Arizona Cardinals vs. Seattle Seahawks
- Venue: Lumen Field in Seattle, WA USA
- Date: Sunday, November 9, 2025
- Betting Odds: Cardinals +251, Seahawks -312
Seattle Seahawks Team Preview
The Seattle Seahawks have been strong in recent games, securing a victory against the Washington Commanders with a score of 38-14. Quarterback Sam Darnold played a significant role, throwing for 330 yards and four touchdowns. This performance highlights the Seahawks’ ability to dominate through the air.
In their home game against the Houston Texans, the Seahawks won 27-19. They gained 198 passing yards and 118 rushing yards, showing a balanced offensive attack. Jaxon Smith-Njigba was a key player with 123 receiving yards and a touchdown.
The Seahawks’ defense is also notable, ranking 11th in opponent scores last season. They recovered five fumbles and recorded 45 sacks, placing them sixth in the league. This defensive strength complements their offensive capabilities, making them a well-rounded team.
BTB Betting Pick
The Cardinals are +6.5 against the Seahawks. Arizona has a strong rushing game, ranking 7th, which can keep the game close. Seattle’s defense ranks 11th in opponent scoring, but Arizona’s offense is 12th in scoring. The projected score is Seahawks 24, Cardinals 20. Taking the Cardinals +6.5 is the pick.
The total for the game is set at 45.5. Arizona and Seattle have offenses ranked 12th and 17th in scoring, respectively. Both defenses are middle of the pack, with Seattle’s opponent scoring at 11th and Arizona’s at 14th. The projected total score is 44, so the Under 45.5 is the pick.